(data stored in ACNUC7421 zone)

HOGENOM: LACCS_1_PE1010

ID   LACCS_1_PE1010                       STANDARD;      PRT;   301 AA.
AC   LACCS_1_PE1010; D5H372;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Tyrosine recombinase xerD; (LACCS_1.PE1010).
GN   Name=xerD; OrderedLocusNames=LCRIS_01010;
OS   LACTOBACILLUS CRISPATUS ST1.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=748671;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACCS_1.PE1010.
CC       Lactobacillus crispatus ST1, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D5H372_LACCS
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by
CC       catalyzing the cutting and rejoining of the recombining DNA
CC       molecules. The xerC-xerD complex is essential to convert dimers of
CC       the bacterial chromosome into monomers to permit their segregation
CC       at cell division. It also contributes to the segregational
CC       stability of plasmids (By similarity).
CC   -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two
CC       molecules of xerC and two molecules of xerD (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000045296 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D5H372; -.
DR   EMBL; FN692037; CBL50457.1; -; Genomic_DNA.
DR   RefSeq; YP_003601482.1; NC_014106.1.
DR   ProteinModelPortal; D5H372; -.
DR   GeneID; 9106347; -.
DR   GenomeReviews; FN692037_GR; LCRIS_01010.
DR   KEGG; lcr:LCRIS_01010; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:HAMAP.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:HAMAP.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:HAMAP.
DR   HAMAP; MF_01807; Recomb_XerD; 1; -.
DR   HAMAP; MF_01808; Recomb_XerC; 1; -.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat-core.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_Lambda-type_N.
DR   InterPro; IPR023109; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   InterPro; IPR011932; Recomb_XerD.
DR   InterPro; IPR023009; Tyrosine_recombinase_XerC/XerD.
DR   Gene3D; G3DSA:1.10.150.130; Integrase_recombinase_N; 1.
DR   Gene3D; G3DSA:1.10.443.10; Phage_intgr_like; 1.
DR   Pfam; PF02899; Phage_integr_N; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA_brk_join_enz; 1.
DR   SUPFAM; SSF47823; L_intgrse_like_N; 1.
DR   TIGRFAMs; TIGR02225; Recomb_XerD; 1.
DR   HOGENOMDNA; LACCS_1.PE1010; -.
KW   tyrosine recombinase xerd;
KW   Cell cycle; Cell division; Chromosome partition; Complete proteome;
KW   Cytoplasm; DNA integration; DNA recombination; DNA-binding.
SQ   SEQUENCE   301 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MEKNNLKDQI DDYLRYSQVE RGLSDNTINA YRQDLEEFRT FVENEGMASW PTEASDVDAF
     LARQRDLNKA TSSISRLISS MRKFYQWLAR QNIQKLNPML EIDLPKKERR LPTALSQAEM
     NRLLEQPNTK RKLGIRDRAI LETLYATGMR VSELINLELQ DLHDNLGLVR VLGKGEKERL
     IPISPVALDW IKKYENEVRD PLILQVGKSD EHIFLNNRGK KITRQAIWQM IKKYCQMAAI
     TKDVTPHTLR HTFATHLLEN GADLRVVQEI LGHSDISTTQ IYTNLSQKQI LNVYQKTHPR
     L
//

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