(data stored in SCRATCH3701 zone)

HOGENOM6: LACCS_1_PE6

ID   LACCS_1_PE6                          STANDARD;      PRT;   826 AA.
AC   LACCS_1_PE6; D5H0B8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; (LACCS_1.PE6).
GN   Name=gyrA; OrderedLocusNames=LCRIS_00006;
OS   LACTOBACILLUS CRISPATUS ST1.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=748671;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACCS_1.PE6.
CC       Lactobacillus crispatus ST1, complete genome.
CC       NRRL Y-1140) chromosome F, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:D5H0B8_LACCS
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D5H0B8; -.
DR   EMBL; FN692037; CBL49453.1; -; Genomic_DNA.
DR   RefSeq; YP_003600478.1; NC_014106.1.
DR   GeneID; 9107297; -.
DR   GenomeReviews; FN692037_GR; LCRIS_00006.
DR   KEGG; lcr:LCRIS_00006; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACCS_1.PE6; -.
DR   PRODOM; LACCS_1_PE6.
DR   SWISS-2DPAGE; LACCS_1_PE6.
KW   DNA gyrase, a subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   826 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDENQTQDHR IKNVDLTSMM RSSFLDYAMS VIVARALPDV RDGLKPVQRR ILYGMSELGV
     TPDKPYKKSA RIVGEVMGKF HPHGDSSIYL AMAHMAQDFS YRYMLVDGHG NFGSVDGDEP
     AAMRYTEARM SKIAVEMLRD INKNTIDWQR NYDDTENEPV VLPARIPNLL VNGANGIAVG
     MTTNIPPHNL TEVISGLHML MKNPDATTKD LMKVIPGPDF PTGGIIMGRG GIYRAYESGK
     GNIVVRAKTN IETEKSGRER IIVSEIPFMV NKAELVKKIA DLAREKTIDG ITGVRDESDQ
     TGMRITIDIR RDASASVVLN NLFKQTQMQA NFGMNMVAIV DGAPHFLTLK QMLQYYLDHQ
     EDVVTRRTRF ELAKAEARAH ILEGLRIALD NIDEIVHIIR NSQSSDIAKA TLISRFGLDD
     KQSQAILDMR LVRLTGLERD KVEAEYKELQ AKIADYKDIL AKPERIDQII YDELLDIQKR
     FGDKRRTEIG ASEVVSIEDE DLIEKQNILL TVTHNGYIKR MPIQEFKTQN RGGKGIKGMG
     VQDGDFIEHL IYSSTHDLLL FFTNAGKVYS KKAYEIPEYG RMAKGLPVVN LLQLEKGEKV
     QTVINIPENA DDNYLFFITK MGTVKRTHVS EFSNIRNSGL IALTLKDGDE LSNVLTTDGK
     QNILIGTHLG YAVTFSENDV RAMGRTAAGV RGINLRENDY VVGSGVLGAD DQVLVISEKG
     YGKRTPAAEY PVKGRGGKGI KTANITEKNG PLAGVTIINS NNDVMVITTD GIMIRFKIED
     VSQTGRSTMG VRLIKVNDGS QVASLTIVPT EEEQDQTGDD DEPKNE
//

If you have problems or comments...

PBIL Back to PBIL home page