(data stored in ACNUC7421 zone)

HOGENOM: LACGA_1_PE1

ID   LACGA_1_PE1                          STANDARD;      PRT;   464 AA.
AC   LACGA_1_PE1; Q047F4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (LACGA_1.PE1).
GN   Name=dnaA; OrderedLocusNames=LGAS_0001;
OS   LACTOBACILLUS GASSERI ATCC 33323.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=324831;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACGA_1.PE1.
CC       Lactobacillus gasseri ATCC 33323, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q047F4_LACGA
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q047F4; -.
DR   EMBL; CP000413; ABJ59418.1; -; Genomic_DNA.
DR   RefSeq; YP_813856.1; NC_008530.1.
DR   ProteinModelPortal; Q047F4; -.
DR   STRING; Q047F4; -.
DR   GeneID; 4439757; -.
DR   GenomeReviews; CP000413_GR; LGAS_0001.
DR   KEGG; lga:LGAS_0001; -.
DR   NMPDR; fig|1596.1.peg.1654; -.
DR   eggNOG; COG0593; -.
DR   OMA; QFIQNKE; -.
DR   PhylomeDB; Q047F4; -.
DR   ProtClustDB; PRK00149; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; LACGA_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   464 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDNTVLGGIF LFDLDKFWQF FNAEMKKSYS TVAYNAWFKN TKPISFNKKT KEMIIAVESP
     VAKGYWEKNL ASQLIQEAYA YADMEIQPKF EVAGKEGPER LVTPKPRIKT NQEILEDRRD
     EFAQDLQLNS KYTFDTFVQG EGNKLAAGAA LAVADNPGSF YNPLFIFGGV GLGKTHLMQA
     IGHQMLAEKP HAKVVYIQSE TFVNDFINSI KNKTQAEFRN KYRNCDLLLV DDIQFFSKKE
     GIQEEFFHTF ETLYNDQKQI VMTSDRLPTE IPELSERLVS RFAWGLQVEI TPPDLETRIA
     ILRKKAETDG LAIDDSTLDY IASQVDTNIR ELEGALVKVQ AHATIEREDI NVDLAKEALA
     DLKLVQKNRG LQISKIQEVV ANYFQTSTTE LKGKKRVKQI VVPRQIAMYL SRELTDSSLP
     KIGQEFGGKD HTTVMHACDK ISRALKTDAE IKAAVYDLKA MLEH
//

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