(data stored in SCRATCH3701 zone)

HOGENOM6: LACGA_1_PE6

ID   LACGA_1_PE6                          STANDARD;      PRT;   829 AA.
AC   LACGA_1_PE6; Q047E9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LACGA_1.PE6).
GN   OrderedLocusNames=LGAS_0006;
OS   LACTOBACILLUS GASSERI ATCC 33323.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=324831;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACGA_1.PE6.
CC       Lactobacillus gasseri ATCC 33323, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q047E9_LACGA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q047E9; -.
DR   EMBL; CP000413; ABJ59423.1; -; Genomic_DNA.
DR   RefSeq; YP_813861.1; NC_008530.1.
DR   ProteinModelPortal; Q047E9; -.
DR   SMR; Q047E9; 34-491.
DR   STRING; Q047E9; -.
DR   GeneID; 4438891; -.
DR   GenomeReviews; CP000413_GR; LGAS_0006.
DR   KEGG; lga:LGAS_0006; -.
DR   NMPDR; fig|1596.1.peg.906; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q047E9; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACGA_1.PE6; -.
DR   PRODOM; LACGA_1_PE6.
DR   SWISS-2DPAGE; LACGA_1_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   829 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MANENQPQDH RIRNVDLTHT MRSSFLDYAM SVIVARALPD VRDGLKPVQR RILYGMHELG
     VTPDKQYKKS ARIVGEVMGK FHPHGDSSIY LAMAHMAQDF SYRYMLVDGH GNFGSVDGDE
     PAAMRYTEAK MSKIAVEMLR DINKETIDWQ RNYDDTENEP VVLPARIPNL LVNGASGIAV
     GMTTNIPPHN LAEVISGIHM LMDNPDVTTK DLMKVIPGPD FPTGGIVMGR GGIYRAYETG
     KGNIVVRAKT NIETEKNGRE RIVVSELPYL VNKAELVKKI ADLAREKIID GITGVRDESD
     QTGMRITIDI RRDASASVVL NNLFKETQMQ ANFGMNMVAI VNGAPHFLTL KQMLEYYLHH
     QEDVITRRTK FELKKAEARA HILAGLRIAL DHIDEIIKII RGSQNSDIAK AQLIQNFGLD
     DRQSQAILDM RLVRLTGLER DKIEAEYQDL QAKIADYKDI LAKPERIDEI IYNELLDIQK
     RFGDDRRTKI AEGEAVSIED EDLIEQKDVL LTLTHNGYIK RMPADEFKVQ NRGGRGIKGM
     GVQDDDFINH LIFSSTHDFL LFFTNLGKVY SKKAYEIPEF GRNAKGLPIV NLLELDKGEK
     IQAVINVPEG ADDNYLFFVT KMGTVKRTKV SEFQNIRRSG LIALTLRDGD ELNNVLTTDG
     KQNILIGTHL GYAVTFNEND VRSMGRTAAG VRGINLRDND YVVGSDILEP DSEVLVISEK
     GYGKRTAASE YPVKGRGGKG IKTANITEKN GPLAGVTVVN GDEDIMLITS AGVMIRFDVD
     DVSQTGRATL GVRLIKVDDG AQVASITAVP KANDEDEEAT DEKEPVEEN
//

If you have problems or comments...

PBIL Back to PBIL home page