(data stored in SCRATCH3701 zone)

HOGENOM6: LACH4_1_PE6

ID   LACH4_1_PE6                          STANDARD;      PRT;   827 AA.
AC   LACH4_1_PE6; A8YW46;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase; (LACH4_1.PE6).
GN   OrderedLocusNames=lhv_0006;
OS   LACTOBACILLUS HELVETICUS DPC 4571.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=405566;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACH4_1.PE6.
CC       Lactobacillus helveticus DPC 4571, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A8YW46_LACH4
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A8YW46; -.
DR   EMBL; CP000517; ABX26303.1; -; Genomic_DNA.
DR   RefSeq; YP_001576588.1; NC_010080.1.
DR   ProteinModelPortal; A8YW46; -.
DR   SMR; A8YW46; 33-490.
DR   STRING; A8YW46; -.
DR   GeneID; 5772780; -.
DR   GenomeReviews; CP000517_GR; lhv_0006.
DR   KEGG; lhe:lhv_0006; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACH4_1.PE6; -.
DR   PRODOM; LACH4_1_PE6.
DR   SWISS-2DPAGE; LACH4_1_PE6.
KW   DNA gyrase;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   827 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDDNQTQDRR IRNVDLTSMM RSSFLDYAMS VIVARALPDV RDGLKPVQRR ILYGMSELGV
     TPDKPYKKSA RIVGEVMGKF HPHGDSSIYL AMAHMAQDFS YRYMLVDGHG NFGSVDGDEP
     AAMRYTEARM SKIAAEMLRD INKNTIDWQR NYDDTENEPV VLPARIPNLL INGANGIAVG
     MTTNIPPHNL SEVISGLHML MKNPDATTKD LMKVIPGPDF PTGGIIMGRG GIYRAYESGK
     GNIVVRAETN IETEKSGRER IIVSEIPYMV NKAELVKKIA DLAREKIIDG ITGVRDESDQ
     TGMRITIDIR RDASASVVLN NLFKQTQMQA NFGMNMVAIV DGAPHYLTLK QMLQYYLDHQ
     KDVVTRRTKF ELAKAEARAH ILEGLRIALD NIDEIVHIIR SSHSSDIAKA TLISRFGLDD
     KQSQAILDMR LVRLTGLERD KVEAEYKELQ AKIADYKDIL AKPERIDKII YDELLDIQKR
     FGDKRRTEIG ASEVVSIEDE DLIEKQNILL TVTHNSYIKR MPIQEFKTQN RGGKGIKGMG
     VQDGDFIEHL IYSSTHDMLL FFTNAGKVYS KKAYEIPEYG RMAKGLPVVN LLQLEKGEKV
     QTVINVPEGA DDNYLFFITK MGTVKRTHVS EFSNIRNSGL IALTLRDGDE LSNVLTTDGK
     QNILIGTHLG YAVTFNENDV RAMGRTAAGV RGINLRDHDY VVGSGVLDAD DQVLVISEKG
     YGKRTPAAEY PVKGRGGKGI KTANITEKNG PLAGVIVISK GKDIMVITTD GIMIRFKTKD
     VSQTGRSTMG VRLIKVSDDS QVASLTIVPS EADQDQVDDE DDNDDNE
//

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