(data stored in ACNUC17686 zone)

HOGENOM: LACLM_1_PE323

ID   LACLM_1_PE323                        STANDARD;      PRT;   182 AA.
AC   LACLM_1_PE323; A2RI47;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Thiamine transporter ThiT;AltName: Full=Thiamine ECF
DE   transporter S component ThiT; (LACLM_1.PE323).
GN   Name=thiT; OrderedLocusNames=llmg_0334;
OS   LACTOCOCCUS LACTIS SUBSP. CREMORIS MG1363.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus.
OX   NCBI_TaxID=416870;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACLM_1.PE323.
CC       Lactococcus lactis subsp. cremoris MG1363, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:THIT_LACLM
CC   -!- FUNCTION: Probably a thiamine-binding protein that interacts with
CC       the energy-coupling factor (ECF) ABC-transporter complex. Unlike
CC       classic ABC transporters this ECF transporter provides the energy
CC       necessary to transport a number of different substrates. The
CC       substrates themselves are bound by transmembrane, not
CC       extracytoplasmic soluble proteins.
CC   -!- SUBUNIT: In E.coli forms a stable energy-coupling factor (ECF)
CC       transporter complex composed of a membrane-embedded substrate-
CC       binding protein (S component), two ATP-binding proteins (A and A'
CC       components) and a transmembrane protein (T component) with a
CC       stoichiometry of 1.1:1:1.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Probable).
CC   -!- SIMILARITY: Belongs to the ECF family. Thiamine transporter
CC       (TC 2.A.88) subfamily.
CC   -!- GENE_FAMILY: HOG000013022 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A2RI47; -.
DR   EMBL; AM406671; CAL96940.1; -; Genomic_DNA.
DR   RefSeq; YP_001031688.1; NC_009004.1.
DR   STRING; A2RI47; -.
DR   TCDB; 2.A.88.3.2; vitamin uptake transporter (VUT or ECF) family.
DR   GeneID; 4796873; -.
DR   GenomeReviews; AM406671_GR; llmg_0334.
DR   KEGG; llm:llmg_0334; -.
DR   eggNOG; COG3859; -.
DR   OMA; TPVWIYS; -.
DR   ProtClustDB; CLSK697153; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   InterPro; IPR012651; Thia_Transptr_ThiT/YuaJ.
DR   Pfam; PF09515; Thia_YuaJ; 1.
DR   TIGRFAMs; TIGR02357; Thia_yuaJ; 1.
DR   HOGENOMDNA; LACLM_1.PE323; -.
KW   hypothetical protein;
KW   Cell membrane; Complete proteome; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
SQ   SEQUENCE   182 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSNSKFNVRL LTEIAFMAAL AFIISLIPNT VYGWIIVEIA CIPILLLSLR RGLTAGLVGG
     LIWGILSMIT GHAYILSLSQ AFLEYLVAPV SLGIAGLFRQ KTAPLKLAPV LLGTFVAVLL
     KYFFHFIAGI IFWSQYAWKG WGAVAYSLAV NGISGILTAI AAFVILIIFV KKFPKLFIHS
     NY
//

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