(data stored in ACNUC7421 zone)

HOGENOM: LACLN_1_PE1

ID   LACLN_1_PE1                          STANDARD;      PRT;   454 AA.
AC   LACLN_1_PE1; D8KDK4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (LACLN_1.PE1).
GN   Name=dnaA; OrderedLocusNames=LLNZ_00005;
OS   LACTOCOCCUS LACTIS SUBSP. CREMORIS NZ9000.
OC   Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus.
OX   NCBI_TaxID=746361;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACLN_1.PE1.
CC       Lactococcus lactis (subsp. cremoris, strain NZ9000) chromosome, complet
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D8KDK4_LACLN
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D8KDK4; -.
DR   EMBL; CP002094; ADJ59021.1; -; Genomic_DNA.
DR   ProteinModelPortal; D8KDK4; -.
DR   GenomeReviews; CP002094_GR; LLNZ_00005.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; LACLN_1.PE1; -.
KW   ADJ59021.1824841755old_1320000031;
KW   Chromosomal replication initiator protein dnaA ;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   454 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MASLNENQKF WARVTELARQ SIGKQAYDFF IEPAQLMSVE QDTANILLDS GMKKDYWKKQ
     SDLITTAGFE VFGRMIDYEL YANDELTDIE LRRLNNQSPV DEPLSVAKPT SPLVSGLNEK
     YNFENFVQGP GNRWTLAAAI AVADKPGDTY NPLFIYGGAG LGKTHLMHAI GNQILTDNPT
     ARIKYVSSEN FVNDYVNATR KNQMESFENT YRNLDLLLLD DVQFFSDKEG TKNEFFNTFN
     ALYDKGSQIV LTSDRIPQEL NNLEDRLVSR FSWGLTTDIT APDYETRMAI LLIKSESSHL
     EFPSETLSYI AGQIDSNVRE LEGALNRVEF VARANGISIV DIETASQALR SLKNATQQSL
     SNLTIKKIQD EVANYYHISF SDLVGPKRPK EIAFPRQIAM YLVRELLGTS LPAIGTAFGG
     RDHTTVMYAY KQISDKMKND MDVQKDIDSI KRKF
//

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