(data stored in ACNUC7421 zone)

HOGENOM: LACRG_1_PE1

ID   LACRG_1_PE1                          STANDARD;      PRT;   449 AA.
AC   LACRG_1_PE1; C7T8F3; C8UYA8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
DE   (LACRG_1.PE1).
GN   Name=dnaA; OrderedLocusNames=LGG_00001, LRHM_0001;
OS   LACTOBACILLUS RHAMNOSUS GG.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=568703;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACRG_1.PE1.
CC       Lactobacillus rhamnosus GG, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C7T8F3_LACRG
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC   -!- SIMILARITY: Belongs to the dnaA family.
CC   -!- GENE_FAMILY: HOG000235658 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C7T8F3; C8UYA8; -.
DR   EMBL; AP011548; BAI40528.1; -; Genomic_DNA.
DR   EMBL; FM179322; CAR85896.1; -; Genomic_DNA.
DR   RefSeq; YP_003169747.1; NC_013198.1.
DR   ProteinModelPortal; C7T8F3; -.
DR   STRING; C7T8F3; -.
DR   GeneID; 8423378; -.
DR   GenomeReviews; AP011548_GR; LRHM_0001.
DR   GenomeReviews; FM179322_GR; LGG_00001.
DR   KEGG; lrh:LGG_00001; -.
DR   OMA; DEVAFLI; -.
DR   ProtClustDB; PRK00149; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:HAMAP.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA-dependent DNA replication initiation; IEA:HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:HAMAP.
DR   HAMAP; MF_00377; DnaA_bact; 1; -.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR013317; DnaA_Hda.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   Gene3D; G3DSA:1.10.1750.10; DnaA_C; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; Trp_repress_rep; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
DR   HOGENOMDNA; LACRG_1.PE1; -.
KW   chromosomal replication initiation protein;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding.
SQ   SEQUENCE   449 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPNLEELWAY LNDKFREELT PVGYSTWIQT AKPVKLTQDK LEIEVPASLH KAYWEKNLVT
     KVVEGVYEFA QLEVDPVIMT KDELQPASTH QHQVTDDDDD QQLTFKAKTH LNPKYTFDRF
     VIGKGNQMAH AAALAVAEAP GTTYNPLFIY GGVGLGKTHL MQAIGNLVLE NNPAANIKYV
     TSENFANDFI NSIQTKQQEQ FRQEYRNVDL LLVDDIQFFG DKEATQEEFF HTFNTLYENM
     KQIVLTSDRL PNEIPKLQER LVSRFNKGLS VDVTPPDLET RIAILRNKAN AEDLSIPDDT
     LSYIAGQIES NVRDLEGALV RVQAFSTMKN EDITTSLAAD ALKALKLDDR SGQLTIPQIL
     DAVAKYFQVT VQDLKGKKRV KQIVIPRQIA MYLAREMTDN SLPKIGQEIG GKDHTTVIHA
     HEKIMAAMTT NEDLKAHVVE LRNILKNRG
//

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