(data stored in SCRATCH3701 zone)

HOGENOM6: LACS1_3_PE6

ID   LACS1_3_PE6                          STANDARD;      PRT;   850 AA.
AC   LACS1_3_PE6; Q1WVP0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LACS1_3.PE6).
GN   Name=gyrA; OrderedLocusNames=LSL_0006;
OS   LACTOBACILLUS SALIVARIUS UCC118.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=362948;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACS1_3.PE6.
CC       Lactobacillus salivarius UCC118, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q1WVP0_LACS1
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1WVP0; -.
DR   EMBL; CP000233; ABD98829.1; -; Genomic_DNA.
DR   RefSeq; YP_534912.1; NC_007929.1.
DR   ProteinModelPortal; Q1WVP0; -.
DR   SMR; Q1WVP0; 30-486.
DR   STRING; Q1WVP0; -.
DR   GeneID; 3978247; -.
DR   GenomeReviews; CP000233_GR; LSL_0006.
DR   KEGG; lsl:LSL_0006; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q1WVP0; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACS1_3.PE6; -.
DR   PRODOM; LACS1_3_PE6.
DR   SWISS-2DPAGE; LACS1_3_PE6.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   850 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVDLPNRIKD VDLSKVMRTS FLDYAMSVIV ARALPDVRDG LKPVHRRILY GMNELGVTPD
     KPYKKSARIV GDVMGKFHPH GDSAIYESMV RMAQDFSYRY MLVDGHGNFG SVDGDGAAAM
     RYTEARMSKI TLEMLRDINK DTIDFQPNYD GTEREPVVLP ARFPNLLVNG ATGIAVGMTT
     NIPPHNLGEV ISGIHMLMKN PDVTTADLME AIPGPDFPTG AIVMGKSGIR KAYETGKGTV
     TLRAKVEIDE QANGKQQIVV HELPYMVNKA RLIERIAELA REKKIEGITD VKDESDREGM
     RVTIDVRRDV SASVVLNNLY KLTLMQTTFG FNMLAIVNGT PKILSLKQIL QYYLKHQEEV
     IRRRTEFELK KAKARAHILE GLRIALDHID AIINIIRGSQ SPDVAKDRLM NEYQLSDKQA
     QAILDMRLVR LTGLERDKVE NEYSKTMAAI ADYEDILAKP ERIDKIIYEE LLEIQEKFGD
     ERRTELMVGE VLSIEDEDLI EEENVVVTLT HNGYIKRLPT SDFKAQNRGG RGVQGMGVHD
     DDFIEHLLTT STHDELLFFT NVGKVYRMKA YEIPEYGRTA KGIPVINLLD ISADEKIQTV
     INIPADKVQT DKEMYLFFIT RQGTVKRTSV SEFGNIRKNG LKAITLRDGD ELINVLATDD
     SKNIIIGTHQ GYAVSFDEKD IRSMGRSAAG VRGIRLRDND YVIGSAILEP ESKVFVISEN
     GYGKQTAASE YPIKGRGGKG IKTTNITEKN GPLAGLTTVN GDEDIMVITD KGVMIRFKIS
     DVSETGRATL GVRLINLGAD SIVSTMTKVE PEDENENSEE TTQEVSTEIS DDTKDSDVAR
     LLDAAQKDGE
//

If you have problems or comments...

PBIL Back to PBIL home page