(data stored in SCRATCH3701 zone)

HOGENOM6: LACSS_1_PE6

ID   LACSS_1_PE6                          STANDARD;      PRT;   857 AA.
AC   LACSS_1_PE6; Q38ZR9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (LACSS_1.PE6).
GN   Name=gyrA; OrderedLocusNames=LSA0006; ORFNames=LCA_0006;
OS   LACTOBACILLUS SAKEI SUBSP. SAKEI 23K.
OC   Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
OX   NCBI_TaxID=314315;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LACSS_1.PE6.
CC       Lactobacillus sakei subsp. sakei 23K, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q38ZR9_LACSS
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q38ZR9; -.
DR   EMBL; CR936503; CAI54308.1; -; Genomic_DNA.
DR   RefSeq; YP_394619.1; NC_007576.1.
DR   ProteinModelPortal; Q38ZR9; -.
DR   SMR; Q38ZR9; 33-489.
DR   STRING; Q38ZR9; -.
DR   GeneID; 3778585; -.
DR   GenomeReviews; CR936503_GR; LCA_0006.
DR   KEGG; lsa:LSA0006; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q38ZR9; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LACSS_1.PE6; -.
DR   PRODOM; LACSS_1_PE6.
DR   SWISS-2DPAGE; LACSS_1_PE6.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   857 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MANENGQDGR IENVNLSKTM RKSFLEYAMS VIVARALPDV RDGLKPVQRR ILYGMSELGV
     TPEKPYKKSA RIVGDVMGKY HPHGDSAIYE AMVRMAQEFS YRYMLVDGHG NFGSVDGDGA
     AAMRYTEARM SKMAVEMLRD INKNTIDYVP NYDESEREPA VLPARFPNLL VNGATGIAVG
     MTTNIPPHNL AEVISAIHIL MDNPDATTAD LMDALPGPDF PTGGLVMGKS GIRHAYESGK
     GTITLRAKVD VEVKKNGRER IIVTEIPYMV NKAKLVERIA ELARDKRLEG ITDLNDESDR
     DGMRIVIDVR RDMSASVILN NLYKLTPLQT SFSFNMVAIV NGAPKVLSLK SILEHYLVHQ
     EEVIRRRTEF DLKKAEARAH ILAGLRIALD HIDAIIQIIR SSKTGDTAKV LLMERYDLSD
     KQAQAILDMR LVRLTGLERD KVENEYNNLM ALITDLKDIL AKPERIKKII YDELLEIQSK
     FGDKRRTELL VGEVLSIEDE DLIEEEDVVI ALTHNGYIKR LPASEFKVQN RGGRGIQGMG
     VHDDDFIEHL ISTSTHEVLL FFTNTGKVYR AKGYEIPEYG RTAKGIPIIN LLGINSDERV
     QTVVNIGKEV KPEQALFFIT RLGTVKRTAV GEFANIRSNG LKALTLHEDD ELSNVLMTDG
     QQNIFIGTHN GYAVSFSETA VRSMGRTAAG VRGIRLREGD YVVGSDLLIP GQEILVISEK
     GYGKRTAVSD YPIKGRGGKG VKTANITEKN GPLAGIAAVT GEEDILLITD TGVLIRFKVA
     NVSQTGRATL GVRLIRVDDE AKVATMATVE AEPDEPETQT ATTEPTVPTE NVTDTGLAQV
     DDLLARAEAD QNEPNND
//

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