(data stored in SCRATCH zone)

HOGENOM: LARHH_1_PE100

ID   LARHH_1_PE100                        STANDARD;      PRT;   154 AA.
AC   LARHH_1_PE100; C1D9Y3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=tRNA (LARHH_1.PE100) (cytidine(34)-2'-O)-methyltransferase;
DE   EC=2.1.1 207;AltName: Full=tRNA
DE   (cytidine/uridine-2'-O-)-methyltransferase TrmL; .
GN   Name=trmL; OrderedLocusNames=LHK_00100;
OS   LARIBACTER HONGKONGENSIS HLHK9.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Laribacter.
OX   NCBI_TaxID=557598;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LARHH_1.PE100.
CC       Laribacter hongkongensis HLHK9, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:C1D9Y3_LARHH
CC   -!- FUNCTION: Methylates the ribose at the nucleotide 34 wobble
CC       position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and
CC       tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-
CC       adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + 5-
CC       carboxymethylaminomethyluridine(34) in tRNA(Leu) = S-adenosyl-L-
CC       homocysteine + 5-carboxymethylaminomethyl-2'-O-methyluridine(34)
CC       in tRNA(Leu).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + cytidine(34) in tRNA
CC       = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(34) in tRNA.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase TrmH family. TrmL
CC       subfamily.
CC   -!- GENE_FAMILY: HOG000272756 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C1D9Y3; -.
DR   EMBL; CP001154; ACO73096.1; -; Genomic_DNA.
DR   RefSeq; YP_002794105.1; NC_012559.1.
DR   ProteinModelPortal; C1D9Y3; -.
DR   STRING; C1D9Y3; -.
DR   GeneID; 7755728; -.
DR   GenomeReviews; CP001154_GR; LHK_00100.
DR   KEGG; lhk:LHK_00100; -.
DR   OMA; EAWRQNG; -.
DR   ProtClustDB; CLSK2547562; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0008175; F:tRNA methyltransferase activity; IEA:HAMAP.
DR   HAMAP; MF_01885; tRNA_methyltr_TrmL; 1; -.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR016914; tRNA_cyt/urid_MeTfrase.
DR   PANTHER; PTHR12029:SF26; PTHR12029:SF26; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   PIRSF; PIRSF029256; SpoU_TrmH_prd; 1.
DR   HOGENOMDNA; LARHH_1.PE100; -.
KW   RNA methyltransferase;
KW   Complete proteome; Cytoplasm; Methyltransferase;
KW   S-adenosyl-L-methionine; Transferase; tRNA processing.
SQ   SEQUENCE   154 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLAVVLFEPE IPPNTGNIIR LCANTGCELH LVEPLGFPLE DARLRRAGLD YHEYAALTVH
     KNWAACRQAL VGRRMLAMTT RSSRPAFALA FAPGDVLVFG PESRGLPAEV LADFADSERL
     RLPMLPGQRS MNLSNAVAVT VFEAWRQQGF AGAI
//

If you have problems or comments...

PBIL Back to PBIL home page