(data stored in SCRATCH3701 zone)

HOGENOM6: LAWIP_1_PE781

ID   LAWIP_1_PE781                        STANDARD;      PRT;   820 AA.
AC   LAWIP_1_PE781; Q1MQ89;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LAWIP_1.PE781).
GN   Name=gyrA; OrderedLocusNames=LI0784;
OS   LAWSONIA INTRACELLULARIS PHE/MN1-00.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Lawsonia.
OX   NCBI_TaxID=363253;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LAWIP_1.PE781.
CC       Lawsonia intracellularis PHE/MN1-00 chromosome, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:GYRA_LAWIP
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1MQ89; -.
DR   EMBL; AM180252; CAJ54838.1; -; Genomic_DNA.
DR   RefSeq; YP_595159.1; NC_008011.1.
DR   ProteinModelPortal; Q1MQ89; -.
DR   SMR; Q1MQ89; 27-483.
DR   STRING; Q1MQ89; -.
DR   GeneID; 4060258; -.
DR   GenomeReviews; AM180252_GR; LI0784.
DR   KEGG; lip:LI0784; -.
DR   eggNOG; COG0188; -.
DR   OMA; TSIPPHR; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; LINT363253:LI0784-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LAWIP_1.PE781; -.
DR   PRODOM; LAWIP_1_PE781.
DR   SWISS-2DPAGE; LAWIP_1_PE781.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   820 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSQTEHHISI EQEMRKSYLE YSLSVIIGRA IPDVRDGLKP VHRRILFAQQ ELGNSYTRPP
     KKCARIVGDV IGKYHPHGDS AVYDALVRMA QDFSMRDPLE EGQGNFGSID GDAPAAMRYT
     EVRMSRLASE FLSDIDKETV DFRPNYDNSL EEPIVLPTKV PNLLLNGSSG IAVGMATNIP
     PHNLGELCNA LLKIIDDPDV PIDNLLNIIH GPDFPTGGFI YVGQGLYDAY TKGRGTVKVR
     GKVEIEERKK GAQSIVIREI PFGLNKSSLV EKIAILVNER KIDGIADLRD ESDRKGIRVV
     IELKKGVIPE IIINALYKFT PLETSFGINM LAVVDNRPQL LTIKSALTYF LDHRREVIVR
     RTRFELNKAE ARLHILIGLI HALDHIDEVV NLIRSSSTPA EAKIRLIERF SLSEIQAQSI
     LDMRLQRLTG LEREKLEEEM HELQTKIAWY ESILGDTKIL WGVIRDEVTG IKEMYTTPRR
     TEVIRETLTN IEIEDLIPDD DVVITLSRRG YIKRTNLAIY QQQRRGGKGV AGLHTSEDDF
     VQEFITTTNH QFLLLFTNKG RMHQLKVHQV PEGSRTAKGT HIANIVPLEK EEWVTTILTV
     REFSDNKFFL FATRKGMVKR SSASYYARSR RTGLLAVGLR EDDELIMVKE VTNNDFIVLA
     TAEGFAIRFS CEDVRNMGRG AAGVKGIALR PGDSVVACLI LQEKQDTPAI MTVSNLGYGK
     RTSIDLYRVQ TRGGKGIINF KVTQKTGLVI GAKPVSDDNA LVLLTSTNKI IRMSVDEVRS
     AGRATMGVRL VKLDDGAYVV GFDTVDGTVD DSCDDATINT
//

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