(data stored in SCRATCH3701 zone)

HOGENOM6: LEGPA_2_PE1344

ID   LEGPA_2_PE1344                       STANDARD;      PRT;   863 AA.
AC   LEGPA_2_PE1344; Q5X5E8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, subunit A, type II topoisomerase;
DE   (LEGPA_2.PE1344).
GN   Name=gyrA; OrderedLocusNames=lpp1372;
OS   LEGIONELLA PNEUMOPHILA STR. PARIS.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=297246;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LEGPA_2.PE1344.
CC       Legionella pneumophila str. Paris, complete genome.
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:Q5X5E8_LEGPA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5X5E8; -.
DR   EMBL; CR628336; CAH12523.1; -; Genomic_DNA.
DR   RefSeq; YP_123696.1; NC_006368.1.
DR   ProteinModelPortal; Q5X5E8; -.
DR   SMR; Q5X5E8; 30-522, 535-841.
DR   STRING; Q5X5E8; -.
DR   GeneID; 3119437; -.
DR   GenomeReviews; CR628336_GR; lpp1372.
DR   KEGG; lpp:lpp1372; -.
DR   LegioList; lpp1372; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LEGPA_2.PE1344; -.
DR   PRODOM; LEGPA_2_PE1344.
DR   SWISS-2DPAGE; LEGPA_2_PE1344.
KW   DNA gyrase, subunit A, type II topoisomerase;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   863 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MVYLAKEVLP VNIEDELKQS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMSELGNDWN
     KPYKKSARVV GDVIGKYHPH GDTAVYDTIV RMAQPFSMRY LLIDGQGNFG SVDGDAPAAM
     RYTEVRMSKV AHALLADLDK ETVDFSPNYD ETEFAPVVLP SRIPNLLVNG SSGIAVGMAT
     NIPPHNLTEV INACIALVDE PDTSLEDLME IIPGPDFPTA AIINGRAGII EGYRTGKGRV
     VIRARTEIET DESSGRQSII IQELPYQVNK ARLIERIAEL VRDKKVEGIS GLRDESDKQG
     MRVVIELKRN EVADVVLNNL FAHTQMQNVF GINMVALVDG QPRTLNLKQI LEYFIKHRRE
     VVTRRTIFEL KKARSRAHLL EGLGIALANI DEMIALIKQS PTPQDAKSAL LSKIWQPGLV
     KAMLEKAGSN ASRPDDLTEE YGLHENGYKL SEAQAQAILE LRLHRLTALE QDKIINEFEE
     LLNLIKELLD ILASPERLMQ VIRDELIEIK SQFGDERRTE ITASQEDLTI EDLITEEDVV
     VTLSHQGYVK YQPITAYQAQ RRGGKGKSAT HVKDEDFVER LVIASTHDTL LCFSNHGKLY
     WLKAYQLPQA SRASRGRPII NILPLAEGEE INAMLPVREY KDGSYVFMAT KKGTVKKVPL
     NAFSRPRSNG IIAVDLEEDD SLVGVDITDG TRDIMLFTDA GKVIRFDENK VRPMGRTARG
     VRGIRVEKDQ AVKSLVVVDP NGGTILTATE NGYGKRTHID EYRVSGRGGQ GVISIQVTER
     NGKVVRSLQV TDNDEAMLIT DKGTLVRFKV NELSVIGRNT QGVRLINVSS GETVVGMQKI
     VDLGEELEEA EDSSLNAEDN SDE
//

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