(data stored in SCRATCH3701 zone)

HOGENOM6: LEGPH_1_PE1392

ID   LEGPH_1_PE1392                       STANDARD;      PRT;   871 AA.
AC   LEGPH_1_PE1392; Q5ZVM3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (LEGPH_1.PE1392).
GN   Name=gyrA; OrderedLocusNames=lpg1417;
OS   LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA STR. PHILADELPHIA 1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=272624;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LEGPH_1.PE1392.
CC       Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosom
CC       complete genome.
CC   -!- ANNOTATIONS ORIGIN:Q5ZVM3_LEGPH
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q5ZVM3; -.
DR   EMBL; AE017354; AAU27499.1; -; Genomic_DNA.
DR   RefSeq; YP_095446.1; NC_002942.5.
DR   ProteinModelPortal; Q5ZVM3; -.
DR   SMR; Q5ZVM3; 38-530, 543-849.
DR   STRING; Q5ZVM3; -.
DR   GeneID; 3078366; -.
DR   GenomeReviews; AE017354_GR; lpg1417.
DR   KEGG; lpn:lpg1417; -.
DR   NMPDR; fig|272624.3.peg.221; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LEGPH_1.PE1392; -.
DR   PRODOM; LEGPH_1_PE1392.
DR   SWISS-2DPAGE; LEGPH_1_PE1392.
KW   DNA gyrase, subunit A, type II topoisomerase;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   871 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSKGYIQIMV YLAKEVLPVN IEDELKQSYL DYAMSVIVGR ALPDVRDGLK PVHRRVLFAM
     SELSNDWNKP YKKSARVVGD VIGKYHPHGD TAVYDTIVRM AQPFSMRYML IDGQGNFGSV
     DGDAPAAMRY TEVRMSKVAH ALLADLDKET VDFSPNYDET EFAPVVLPSR IPNLLVNGSS
     GIAVGMATNI PPHNLTEVIN ACIALVDEPD TSLEDLMEII PGPDFPTAAI INGRAGIIEG
     YRTGKGRVVI RARTEIETDE SSGRQSIIIQ ELPYQVNKAR LIERIAELVR DKKIEGISGL
     RDESDKQGMR VVIELKRNEV ADVVLNNLFA HTQMQNVFGI NMVALVDGQP RTLNLKQILE
     YFIKHRREVV TRRTIFELKK ARSRAHLLEG LGIALANIDE MIALIKQSPT PQDAKSALLS
     KIWQPGLVKA MLEKAGSNAS RPDDLTEEYG LHESGYKLSE AQAQAILELR LHRLTALEQD
     KIINEFEELL NLIKELLDIL ASPERLMQVI RDELIEIKSQ FGDERRTEIT ASQEDLTIED
     LITEEDVVVT LSHQGYVKYQ PITAYQAQRR GGKGKSATHV KDEDFVERLV IASTHDTLLC
     FSNHGKLYWL KAYQLPQASR ASRGRPIINI LPLAEGEEIN AMLPVREYKD GSYVFMATKK
     GTVKKVPLNA FSRPRSNGII AVDLEEDDSL VGVDITDGAR DIMLFTDAGK VIRFDESKVR
     PMGRTARGVR GIRVEKDQAV KSLVVVDPSG GTILTATENG YGKRTHIDEY RVSGRGGQGV
     ISIQVTERNG KVVRSLQVTD NDEAMLITDK GTLVRFKVNE LSVIGRNTQG VRLINVSSGE
     AVVGMQKIVD LGEELEEAED SSLNAEDSSD E
//

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