(data stored in ACNUC7421 zone)

HOGENOM: LEINT1_1_PE2293

ID   LEINT1_1_PE2293                      STANDARD;      PRT;   364 AA.
AC   LEINT1_1_PE2293; Q8F2A8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Methylthioribose-1-phosphate isomerase; Short=M1Pi;
DE   Short=MTR-1-P isomerase; EC=5.3.1 23;AltName:
DE   Full=S-methyl-5-thioribose-1-phosphate isomerase; (LEINT1_1.PE2293).
GN   Name=mtnA; OrderedLocusNames=LA_2868;
OS   LEPTOSPIRA INTERROGANS SEROVAR LAI STR. 56601.
OC   Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira.
OX   NCBI_TaxID=189518;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LEINT1_1.PE2293.
CC       Leptospira interrogans serovar Lai str. 56601 chromosome chromosome I,
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:MTNA_LEPIN
CC   -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1-
CC       phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-methyl-5-thio-alpha-D-ribose 1-phosphate =
CC       S-methyl-5-thio-D-ribulose 1-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via
CC       salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose
CC       1-phosphate: step 1/6.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family. MtnA subfamily.
CC   -!- GENE_FAMILY: HOG000224730 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q8F2A8; -.
DR   EMBL; AE010300; AAN50067.1; -; Genomic_DNA.
DR   RefSeq; NP_713049.1; NC_004342.2.
DR   ProteinModelPortal; Q8F2A8; -.
DR   GeneID; 1152211; -.
DR   GenomeReviews; AE010300_GR; LA_2868.
DR   KEGG; lil:LA_2868; -.
DR   NMPDR; fig|189518.1.peg.2868; -.
DR   OMA; RPRNQGA; -.
DR   ProtClustDB; CLSK574624; -.
DR   BioCyc; LINT189518:LA2868-MON; -.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01678; Salvage_MtnA; 1; -.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR005251; IF-2BI_MTNA.
DR   InterPro; IPR011559; Initiation_fac_2B_a/b/d.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   TIGRFAMs; TIGR00524; EIF-2B_rel; 1.
DR   TIGRFAMs; TIGR00512; Salvage_mtnA; 1.
DR   HOGENOMDNA; LEINT1_1.PE2293; -.
KW   translation initiation factor 2B;
KW   Amino-acid biosynthesis; Complete proteome; Isomerase;
KW   Methionine biosynthesis; Reference proteome.
SQ   SEQUENCE   364 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MQESGLKPIL WKNKELILLD QRVLPGTTSY ITAKTLEDCI FAIREMVVRG APAIAITGAF
     GITLYWNSLV SKPSFSELKL KLSELLESRP TAVNLRLAIE EFSSRFPESN YSSFSLEEIQ
     KGAEELALFM LSEDLENNLT LSKYALSLFP KQPSSLNIIT HCNTGALATA GHGTALGVIR
     SLRDAGHSLT VFADETRPYL QGARLTAWEL QEEKIQSFLI TDNMAGWVMS SRKIDAVIVG
     ADRIASNGDT ANKIGTYPLA IVAKHHGVPF YVAATAKSMD FRIPNGSYIP IEMRKEEEIT
     SFGFLKDSDG KPLLKEGVIA PKGMKALNPS FDVTPASLIT GIITEKGIVS PVTEENLKKI
     FQLI
//

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