(data stored in ACNUC14511 zone)

HOGENOM: LEMAJ1_22_PE135

ID   LEMAJ1_22_PE135                      STANDARD;      PRT;   362 AA.
AC   LEMAJ1_22_PE135; Q4QBL1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=Farnesyl pyrophosphate synthase; EC=2.5.1.1; EC=2.5.1 10;
DE   (LEMAJ1_22.PE135).
GN   Name=FPPS; ORFNames=LMJF_22_1360;
OS   LEISHMANIA MAJOR STRAIN FRIEDLIN.
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmania.
OX   NCBI_TaxID=347515;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LEMAJ1_22.PE135.
CC       Leishmania major strain Friedlin complete genome, chromosome 22
CC       chromosome II, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q4QBL1_LEIMA
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC   -!- GENE_FAMILY: HOG000160912 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Leishmania_major_strain_friedl;FPPS;CAJ04700.1.
DR   UniProtKB/Swiss-Prot; Q4QBL1; -.
DR   EMBL; FR796418; CAJ04700.1; -; Genomic_DNA.
DR   RefSeq; XP_001683287.1; XM_001683235.1.
DR   ProteinModelPortal; Q4QBL1; -.
DR   SMR; Q4QBL1; 4-362.
DR   GeneID; 5651895; -.
DR   GenomeReviews; FR796418_GR; FPPS.
DR   KEGG; lma:LmjF22.1360; -.
DR   EuPathDB; EupathDB:LmjF.22.1360; -.
DR   OMA; ENKTSHY; -.
DR   PhylomeDB; Q4QBL1; -.
DR   ProtClustDB; CLSZ2438621; -.
DR   BRENDA; 2.5.1.10; 19061.
DR   GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:EC.
DR   GO; GO:0004337; F:geranyltranstransferase activity; IEA:EC.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR008949; Terpenoid_synth.
DR   Gene3D; G3DSA:1.10.600.10; Terpenoid_synth; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SUPFAM; SSF48576; Terpenoid_synth; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
DR   HOGENOMDNA; LEMAJ1_22.PE135; -.
KW   FPPS4699.1000047545old_1320000031; CAJ04700.1000044101old_1320000031;
KW   farnesyl pyrophosphate synthase;
KW   Complete proteome; Isoprene biosynthesis; Reference proteome;
KW   Transferase.
SQ   SEQUENCE   362 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAHMERFQKV YEEVQEFLLG DAEKRFEMDV HRKGYLKSMM DTTCLGGKYN RGLCVVDVAE
     AMAKDTQMDA AAMERVLHDA CVCGWMIEML QAHFLVEDDI MDHSKTRRGK PCWYLHPGVT
     AQVAINDGLI LLAWATQMAL HYFADRPFLA EVLRVFHDVD LTTTIGQLYD VTSMVDSAKL
     DAKVAHANTT DYVEYTPFNH RRIVVYKTAY YTYWLPLVMG LLVSGTLEKV DKKATHKVAM
     VMGEYFQVQD DVMDCFTPPE KLGKIGTDIE DAKCSWLAVT FLTTAPAEKV AEFKANYGST
     DPAAVAVIKQ LYTEQNLLAR FEEYEKAVVA EVEQLIAALE AQNAAFAASV KVLWSKTYKR
     QK
//

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