(data stored in SCRATCH3701 zone)

HOGENOM6: LEPBA_1_PE9

ID   LEPBA_1_PE9                          STANDARD;      PRT;   843 AA.
AC   LEPBA_1_PE9; B0S912;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LEPBA_1.PE9).
GN   Name=gyrA; OrderedLocusNames=LBF_0009;
OS   LEPTOSPIRA BIFLEXA SEROVAR PATOC STRAIN 'PATOC 1 (AMES)'.
OC   Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira.
OX   NCBI_TaxID=355278;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LEPBA_1.PE9.
CC       Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)' chromosome
CC       chromosome I, complete sequence.
CC   -!- ANNOTATIONS ORIGIN:GYRA_LEPBA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the topoisomerase GyrA/ParC subunit family.
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B0S912; -.
DR   EMBL; CP000777; ABZ92556.1; -; Genomic_DNA.
DR   RefSeq; YP_001961134.1; NC_010842.1.
DR   ProteinModelPortal; B0S912; -.
DR   SMR; B0S912; 57-514.
DR   STRING; B0S912; -.
DR   GeneID; 6387243; -.
DR   GenomeReviews; CP000777_GR; LBF_0009.
DR   KEGG; lbf:LBF_0009; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   BioCyc; LBIF355278:LBF_0009-MON; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   HAMAP; MF_01897; GyrA; 1; -.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 2.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LEPBA_1.PE9; -.
DR   PRODOM; LEPBA_1_PE9.
DR   SWISS-2DPAGE; LEPBA_1_PE9.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   843 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTEQNGQENE SNKTLALNLS GRPDVAGALK AGVRVIPVEI EDQMKEAYLD YAMSVIVGRA
     LPDVRDGLKP VHRRVLHAMN ERAWRSDRPY VKSAKIVGEV IGNYHPHGDS AVYETMVRMA
     QTFSMRETLI DGQGNFGSVD GDNAAAYRYT EARLTKLAEE LLKDIEKNTV SFSPNFDDTR
     QQPDVLPANF PNILVNGSTG IAVGMATNIP PHNLKEAVNA VIALIQNPDI TLPELMKILP
     GPDFPTGGTI IGGEGLYQAY ATGKGSIRIR SKVDIIENNK GREIIVIHEI PYQVNKKNML
     EKIGDLVNEK IIEGISEILD LSDRKGIRVE IHVKKDANAQ VILNQLFKLT QLQVSYGITM
     LAILDNRPKI FSLKEILKSY AEHRREVVVK RTEFDLDKAQ KRAHILEGLR IALENIDEVI
     RIIRASKDVR EAQSSLMATF SLSELQADAI LEMRLQRLTS LEVQKIIDEL EQVRILIADL
     EDILSKPDRV KSIICDELGK VSQSFGNTRT TEISLESLES STFNAEDLIA DEEVVVQLSE
     DMFIKRLPMD TFRRQKRGGK GVQGISTKRE DFVKKLSSAM THDNLMLFSN KGRAFLLKVY
     ELPIATKEAR GKSLKAVINL NDDEIITSLF TFRNFDESYL LMVTREGFVK KIQLDEFTNT
     KKSGIIAIGL RDGDELIDVI ANPNNYDVFI GSKNGLAIRM NLNELRSQGR TASGVTAMKL
     EDDDSIAGIT KVEPNTNLFC ISENGFGKRT DFEEFSTKGR GGKGMTYLKI GEKNGRAVGI
     SSVKEEDELL VITQSGMAIR VEVKTISMVG RSAMGVKVVN TKDEDFVKDF AVVRESDSDS
     AES
//

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