(data stored in SCRATCH3701 zone)

HOGENOM6: LEUMM_2_PE6

ID   LEUMM_2_PE6                          STANDARD;      PRT;   848 AA.
AC   LEUMM_2_PE6; Q040E4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (LEUMM_2.PE6).
GN   OrderedLocusNames=LEUM_0006;
OS   LEUCONOSTOC MESENTEROIDES SUBSP. MESENTEROIDES ATCC 8293.
OC   Bacteria; Firmicutes; Lactobacillales; Leuconostoc.
OX   NCBI_TaxID=203120;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS LEUMM_2.PE6.
CC       Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293, complete geno
CC       complete sequence.
CC   -!- ANNOTATIONS ORIGIN:Q040E4_LEUMM
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q040E4; -.
DR   EMBL; CP000414; ABJ61178.1; -; Genomic_DNA.
DR   RefSeq; YP_817551.1; NC_008531.1.
DR   ProteinModelPortal; Q040E4; -.
DR   SMR; Q040E4; 31-487.
DR   STRING; Q040E4; -.
DR   GeneID; 4421983; -.
DR   GenomeReviews; CP000414_GR; LEUM_0006.
DR   KEGG; lme:LEUM_0006; -.
DR   NMPDR; fig|203120.1.peg.759; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q040E4; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; LEUMM_2.PE6; -.
DR   PRODOM; LEUMM_2_PE6.
DR   SWISS-2DPAGE; LEUMM_2_PE6.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   848 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSELNDSRIK NANLSEQMKT SFLSYAMSVI VARALPDVRD GMKPVHRRIL YSMIEQGNTP
     DKPHKKSARI VGDVMGKYHP HGDSAIYESM VRMAQPFSYR HMLIDGHGNF GSVDGDGAAA
     MRYTEARLSK VAMEMVRDLN KDTVNFIPNY DGEEREPEVL PARFPNLLVN GATGIAVGMT
     TNIPTHNLAE VISALHILMN NPEATTADLM EALPGPDFPT GGIVMGKSGI RRAYETGRGT
     VTVRAKVDIE QLKSGKEQIV VTELPYAVNK ARLIERISEL ARDKKIEGIT GIRDESDREG
     LRISIDVRRD ASASVILNNL YKQTLLQTSF SFNMLAIDHG APKTMSLKEI LVAYLAHQRE
     VIRRRTVFEL QKAQARAHIL EGLRIALDHI DEIITIIRSS KTSEEAKTRL INGYALSDKQ
     AQAILDMRLV RLTGLERDKI EEEYQKLVAL IADLKDILAH EERVDEIIYN ELLEIQTKFG
     DKRRTELQVG DVLSIEDEDL IEEEDVIVTL TNSGYIKRVA TGEFKAQNRG GRGVQGMNVH
     DEDFVDQMIS TSTHDTLLFF TNKGKVYRMK GYEVPEYGRQ AKGIPVVNLL NFEGNEKIQT
     VINVRGEAGE SNDYLFFVTR LGVVKRTAVK EFANIRTNGL KALTLHDDDE VLSVQITDGT
     QNIIIATHNG YSVSFAENDV RVMGRSAAGV RGIRLREGDL VVGSDVLEKD HNVLIITEKG
     YGKQTPVSEY PIKGRGGKGI KTANITEKNG PLAGMTIVSG QEDIMVTTTQ GVMIRFNVDS
     VSQTGRATLG VRLIRLEGNA KVATLAKVEH EEVLEDVSRE TSDKAPLDEQ QIDQVSELLD
     RAQDDTDK
//

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