(data stored in ACNUC10243 zone)

HOGENOM: MACMU11_106_PE4

ID   MACMU11_106_PE4                      STANDARD;      PRT;   330 AA.
AC   MACMU11_106_PE4; Q28521;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP
DE   A1;AltName: Full=Helix-destabilizing protein;AltName:
DE   Full=Single-strand-binding protein;AltName: Full=hnRNP core protein A1;
DE   (MACMU11_106.PE4).
GN   Name=HNRNPA1; Synonyms=HNRPA1;
OS   MACACA MULATTA.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini;
OC   Cercopithecoidea; Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MACMU11_106.PE4.
CC       Macaca mulatta chromosome 11 MMUL_1 partial sequence 102002898..1029401
CC       annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:ROA1_MACMU
CC   -!- FUNCTION: Involved in the packaging of pre-mRNA into hnRNP
CC       particles, transport of poly(A) mRNA from the nucleus to the
CC       cytoplasm and may modulate splice site selection.
CC   -!- SUBUNIT: Identified in the spliceosome C complex. Identified in a
CC       mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG,
CC       HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU,
CC       HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4,
CC       PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2,
CC       YBX1 and untranslated mRNAs. Interacts with SEPT6 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=Localized in
CC       cytoplasmic mRNP granules containing untranslated mRNAs (By
CC       similarity). Shuttles continuously between the nucleus and the
CC       cytoplasm along with mRNA. Component of ribonucleosomes.
CC   -!- PTM: Sumoylated (By similarity).
CC   -!- SIMILARITY: Contains 2 RRM (RNA recognition motif) domains.
CC   -!- GENE_FAMILY: HOG000234442 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Macaca_mulatta;ENSMMUG00000031613;ENSMMUT00000045769;ENSMMUP00000038816.
DR   EMBL; M84334; - ;
DR   UniProtKB/Swiss-Prot; Q28521; -.
DR   EMBL; M84334; AAB01436.1; -; mRNA.
DR   PIR; S30192; S30192.
DR   RefSeq; NP_001036248.1; NM_001042783.1.
DR   UniGene; Mmu.17270; -.
DR   ProteinModelPortal; Q28521; -.
DR   SMR; Q28521; 8-190.
DR   STRING; Q28521; -.
DR   GeneID; 702977; -.
DR   KEGG; mcc:702977; -.
DR   CTD; 3178; -.
DR   eggNOG; prNOG15016; -.
DR   GeneTree; ENSGT00550000074566; -.
DR   InParanoid; Q28521; -.
DR   OrthoDB; EOG4HQDKF; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR021662; HnRNPA1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait.
DR   InterPro; IPR000504; RRM_dom.
DR   Gene3D; G3DSA:3.30.70.330; a_b_plait_nuc_bd; 1.
DR   Pfam; PF11627; HnRNPA1; 1.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   PROSITE; PS50102; RRM; 2.
DR   HOGENOMDNA; MACMU11_106.PE4; -.
KW   ENSMMUG000000316135old_1320000031; ENSMMUP000000388161old_1320000031;
KW   M84334;
KW   Acetylation; Complete proteome; Cytoplasm; Isopeptide bond;
KW   Methylation; mRNA processing; mRNA splicing; mRNA transport; Nucleus;
KW   Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein;
KW   RNA-binding; Spliceosome; Transport; Ubl conjugation.
SQ   SEQUENCE   330 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVAMRDPN TKRSRGFRFV
     TYATVEEVDA AMNARPHKVD GRVVEPKTAV SREDSQRPGA HLTVKKIFVG GIKEDTEEHH
     LRDYFEQYGK IEVIEIMTDR GSGKKRGFAF VTFDDHDSVD KTVIQKYHTV NGHNCEVRKA
     LSKQEMASAS SSQRGRSGSG NFGGGRGGGF GGNDNFGRGG NFSGRGGFGG SRGGGGCGGS
     GDGYNGFGND GSNFGGGGSY NDFGNYNNQS SNFGPMKGGN FGGRSSGSYG GGGQYFAKPR
     NQGEESQRSD REATGYNRFV NSAKHSGGRA
//

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