(data stored in ACNUC2803 zone)

HOVERGEN: MAGB5_HUMAN

ID   MAGB5_HUMAN             Reviewed;         275 AA.
AC   Q9BZ81;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 2.
DT   03-NOV-2009, entry version 47.
DE   RecName: Full=Melanoma-associated antigen B5;
DE   AltName: Full=MAGE-B5 antigen;
DE   AltName: Full=Cancer/testis antigen 3.3;
DE            Short=CT3.3;
GN   Name=MAGEB5;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15772651; DOI=10.1038/nature03440;
RA   Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA   Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A.,
RA   Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G.,
RA   Jones M.C., Hurles M.E., Andrews T.D., Scott C.E., Searle S.,
RA   Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R.,
RA   Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L.,
RA   Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A.,
RA   Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S.,
RA   Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R.,
RA   Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M.,
RA   Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N.,
RA   Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D.,
RA   Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W.,
RA   Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C.,
RA   Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C.,
RA   Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA   Corby N., Connor R.E., David R., Davies J., Davis C., Davis J.,
RA   Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S.,
RA   Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I.,
RA   Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L.,
RA   Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P.,
RA   Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S.,
RA   Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A.,
RA   Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J.,
RA   Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J.,
RA   Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S.,
RA   de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z.,
RA   Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C.,
RA   Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W.,
RA   Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA   Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA   McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T.,
RA   Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I.,
RA   Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N.,
RA   Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J.,
RA   Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E.,
RA   Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S.,
RA   Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA   Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA   Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA   Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T.,
RA   Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S.,
RA   Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L.,
RA   Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A.,
RA   Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L.,
RA   Williams G., Williams L., Williamson A., Williamson H., Wilming L.,
RA   Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H.,
RA   Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A.,
RA   Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA   Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A.,
RA   Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T.,
RA   Gibbs R.A., Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence of the human X chromosome.";
RL   Nature 434:325-337(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 125-235.
RC   TISSUE=Blood;
RX   MEDLINE=20321428; PubMed=10861452;
RX   DOI=10.1002/1097-0215(20000701)87:1<55::AID-IJC8>3.3.CO;2-A;
RA   Lucas S., De Plaen E., Boon T.;
RT   "MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE
RT   family with tumor-specific expression.";
RL   Int. J. Cancer 87:55-60(2000).
CC   -!- TISSUE SPECIFICITY: Expressed in testis. Not expressed in other
CC       normal tissues, but is expressed in tumors of different
CC       histological origins.
CC   -!- SIMILARITY: Contains 1 MAGE domain.
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CC   -!- GENE_FAMILY: HBG006315 [ FAMILY / ALN / TREE ]
DR   EMBL; AF333705; AAK00357.1; -; Genomic_DNA.
DR   IPI; IPI00887293; -.
DR   UniGene; Hs.224079; -.
DR   Ensembl; ENST00000379029; ENSP00000368315; ENSG00000188408; Homo sapiens.
DR   GeneCards; GC0XP026144; -.
DR   H-InvDB; HIX0056572; -.
DR   H-InvDB; HIX0056590; -.
DR   HGNC; HGNC:23795; MAGEB5.
DR   MIM; 300466; gene.
DR   PharmGKB; PA134913823; -.
DR   HOVERGEN; Q9BZ81; -.
DR   OMA; DERANSR; -.
DR   ArrayExpress; Q9BZ81; -.
DR   CleanEx; HS_MAGEB5; -.
DR   Genevestigator; Q9BZ81; -.
DR   InterPro; IPR002190; MAGE.
DR   PANTHER; PTHR11736; MAGE; 1.
DR   Pfam; PF01454; MAGE; 1.
DR   PROSITE; PS50838; MAGE; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q9BZ81.
DR   SWISS-2DPAGE; Q9BZ81.
KW   Complete proteome; Tumor antigen.
FT   CHAIN         1    275       Melanoma-associated antigen B5.
FT                                /FTId=PRO_0000156716.
FT   DOMAIN       40    239       MAGE.
SQ   SEQUENCE   275 AA;  31906 MW;  57EDE75D76D07004 CRC64;
     MTSAGVFNAG SDERANSRDE EYPCSSEVSP STESSCSNFI NIKVGLLEQF LLYKFKMKQR
     ILKEDMLKIV NPRYQNQFAE IHRRASEHIE VVFAVDLKEV NPTCHLYDLV SKLKLPNNGR
     IHVGKVLPKT GLLMTFLVVI FLKGNCANKE DTWKFLDMMQ IYDGKKYYIY GEPRKLITQD
     FVRLTYLEYH QVPCSYPAHY QFLWGPRAYT ETSKMKVLEY LAKVNDIAPG AFSSQYEEAL
     QDEEESPSQR CSRNWHYCSG QDCLRAKFSS FSQPY
//

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