(data stored in SCRATCH3701 zone)

HOGENOM6: MECIC1_2_PE3990

ID   MECIC1_2_PE3990                      STANDARD;      PRT;   933 AA.
AC   MECIC1_2_PE3990; E8TB11;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (MECIC1_2.PE3990).
GN   OrderedLocusNames=Mesci_4052;
OS   MESORHIZOBIUM CICERI BIOVAR BISERRULAE WSM1271.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=765698;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MECIC1_2.PE3990.
CC       Mesorhizobium ciceri biovar biserrulae WSM1271 chromosome, complete
CC       genome.
CC   -!- ANNOTATIONS ORIGIN:E8TB11_MESCW
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E8TB11; -.
DR   EMBL; CP002447; ADV13165.1; -; Genomic_DNA.
DR   RefSeq; YP_004143215.1; NC_014923.1.
DR   GeneID; 10119541; -.
DR   GenomeReviews; CP002447_GR; Mesci_4052.
DR   KEGG; mci:Mesci_4052; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; MECIC1_2.PE3990; -.
DR   PRODOM; MECIC1_2_PE3990.
DR   SWISS-2DPAGE; MECIC1_2_PE3990.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   933 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTDQKTPRGA DGGPTGIEPI SIVEEMQRSY LDYAMSVIVS RALPDVRDGL KPVHRRILFA
     AHESGYHWNR KYVKSARPVA DVMGKYHPHG DASIYDALVR MAQDWSLRVP LIDGQGNFGS
     IDGDPPAAMR YTEARLTKVA HELLEDIDKD TVDFQDTYDA SGSEPKVLPA RFPNLLVNGS
     GGIAVGMATN IPPHNLGEVC NGAIAIIDNP AIDLPALMEI IPGPDFPTGG IVLGRSGIYS
     AYSTGRGSIV MRGRVNIEQR GNDRESIIIT EVPYQVNKSS MIEKMAELVR DKRIEGISDI
     RDESDRQGYR VVIELKRDAV ADVILNQLYR FTPLQTSFGA NMVALNGGKP EVMNLTDMLK
     AFVAFREEVI TRRTKFLLRK ARDRAHVLVG LAIAVANIDE VIKLIRTAPD PQTAREQLME
     RRWPSGDVES LILLIDDPRH RINEDGTYNL SEEQARAILE LRLQRLTALG RDEIADELNT
     IGAEIIDYLD ILSSRARVQQ IVKDELAAVR DEFGTPRRTE LTDGGSDMED EDLIQREDMV
     VTVSHSGYIK RVPLSLYRAQ RRGGKGRSGM STKEEDFVTR LFVANTHTPV LFFSSRGIVY
     KEKVWRLPIG NPQSRGKALI NMLPLEQGER ITTIMPLPED EASWGELYVM FATTRGTVRR
     NDLSDFVQVN RNGKIAMKLE EEGDEILGVE TCTDKDDVLL TASSGQCIRF SVGDVRVFQS
     RNSVGVRGIT MAETDRIISM SVIEHVDASP AERAAYLKRA AAERRLATET AGEEEEIALT
     NEEIGEETEL SDSRYEELKA HEQYVLTVTE FGYGKRSSSY DFRLTGRGGK GIRATDVSKA
     AEIGRLVATF PVGNDDQIML VSDGGTVIRV PVNGIRFASR ATKGVTIFNT AEGEKVVSVE
     RISEPQADEE SEETVEGGAD AAAASDAGPE GAD
//

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