(data stored in SCRATCH3701 zone)

HOGENOM6: METEA_2_PE4630

ID   METEA_2_PE4630                       STANDARD;      PRT;   911 AA.
AC   METEA_2_PE4630; C5ATS1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, subunit A (METEA_2.PE4630) (Type II
DE   topoisomerase); EC=5.99.1 3; .
GN   Name=gyrA; OrderedLocusNames=MexAM1_META1p5016;
OS   METHYLOBACTERIUM EXTORQUENS AM1.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Methylobacteriaceae; Methylobacterium.
OX   NCBI_TaxID=272630;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS METEA_2.PE4630.
CC       Methylobacterium extorquens AM1, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C5ATS1_METEA
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C5ATS1; -.
DR   EMBL; CP001510; ACS42620.1; -; Genomic_DNA.
DR   RefSeq; YP_002965897.1; NC_012808.1.
DR   ProteinModelPortal; C5ATS1; -.
DR   SMR; C5ATS1; 41-523.
DR   STRING; C5ATS1; -.
DR   GeneID; 7994783; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; METEA_2.PE4630; -.
DR   PRODOM; METEA_2_PE4630.
DR   SWISS-2DPAGE; METEA_2_PE4630.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   911 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADDNDQPGA GTPPPATDIK PVSITDEMRR SYLDYAMSVI VSRALPDARD GLKPVHRRIL
     FAAHESGHLP ERRYVKSARI VGDVIGKYHP HGDQSIYDAL VRMAQDFSMR LMLIDGQGNF
     GSVDGDPAAA MRYTESRLAK PASALLSDID KNTVDFQANY DGEHEEPTVL PARFPNLLVN
     GAGGIAVGMA TNIPPHNLGE LIDACIALID DPSLTIEALN EIVPGPDFPT GGLILGRAGT
     RQAYATGRGS IIMRAKSHIE ELRKEREALI FTEIPYQVNK ATLVEKIAEL VKEKRVEGIS
     DLRDESDRDG MRIVVEIKRD AMAEVVLNQL YRYTPLQSSF GCNMVALNGG RPELMNLKDL
     LLAFNDFREE VVSRRTKFLL NKARERAHVL CGLAIAVANI DEVIRLIRTS PDPNTAREAL
     MARDWPAHDI APLIALVDDP RYRVAEDGTY RLSEIQARAI LDLRLQRLTA LGRDEVGDEL
     KKLADEIADY LDILRSRVRI QAIVKTELAE VRALFATPRK TEIIDSDFSV EDEDLIARED
     MVVTVSHAGY VKRVPLSTYR AQRRGGKGRS GMATRDEDFV TRLFVASTHT PVLFFSDQGQ
     AYKEKVWRLP MAAPNARGKA LVNILHLQNE GERISTIMPL PEDETSWDTL DVMFATASGN
     VRRNKLSDFT TVNRNGKIAM KLDPGDHIVH VEICRPEQNV LLTTALGQCI RFPVEDVRVF
     KGRDSTGVRG INLAQDDKVI SMAILNAFDA SPEERAGYLK MRRAVIGDAG EAEAEPAEAE
     EASEASAISL ERYNEMGAAE QFVLTLSDRG FGKRSSSYEY RTSGRGGKGI TAMRVNARNG
     NLVASFPVEA SDQIMLVTNA GQLIRVPVDD IRIVGRASQG VTVFNTDKAE RVVSVEHIEG
     EDENENGEEA V
//

If you have problems or comments...

PBIL Back to PBIL home page