(data stored in ACNUC10043 zone)

HOGENOM: METEZ_1_PE101

ID   METEZ_1_PE101                        STANDARD;      PRT;   497 AA.
AC   METEZ_1_PE101; D7E611;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable cobyric acid synthase; (METEZ_1.PE101).
GN   Name=cobQ; OrderedLocusNames=Metev_0101;
OS   METHANOHALOBIUM EVESTIGATUM Z-7303.
OC   Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales;
OC   Methanosarcinaceae; Methanohalobium.
OX   NCBI_TaxID=644295;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS METEZ_1.PE101.
CC       Methanohalobium evestigatum Z-7303 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:D7E611_METEZ
CC   -!- FUNCTION: Catalyzes amidations at positions B, D, E, and G on
CC       adenosylcobyrinic A,C-diamide. NH(2) groups are provided by
CC       glutamine, and one molecule of ATP is hydrogenolyzed for each
CC       amidation (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC   -!- SIMILARITY: Belongs to the CobB/CobQ family. CobQ subfamily.
CC   -!- SIMILARITY: Contains 1 GATase cobBQ-type domain.
CC   -!- GENE_FAMILY: HOG000224803 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D7E611; -.
DR   EMBL; CP002069; ADI73033.1; -; Genomic_DNA.
DR   RefSeq; YP_003725829.1; NC_014253.1.
DR   GeneID; 9345712; -.
DR   GenomeReviews; CP002069_GR; Metev_0101.
DR   KEGG; mev:Metev_0101; -.
DR   OMA; TKSTRGD; -.
DR   GO; GO:0015420; F:cobalamin-transporting ATPase activity; IEA:HAMAP.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00028; CobQ; 1; -.
DR   InterPro; IPR002586; CbiA_P_synth.
DR   InterPro; IPR017929; CobB/CobQ_GATase.
DR   InterPro; IPR004459; CobQ_synth.
DR   InterPro; IPR011698; GATase_3.
DR   Pfam; PF01656; CbiA; 1.
DR   Pfam; PF07685; GATase_3; 1.
DR   TIGRFAMs; TIGR00313; CobQ; 1.
DR   PROSITE; PS51274; GATASE_COBBQ; 1.
DR   HOGENOMDNA; METEZ_1.PE101; -.
KW   cobyric acid synthase CobQ;
KW   Cobalamin biosynthesis; Complete proteome; Glutamine amidotransferase.
SQ   SEQUENCE   497 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MKSKTNGDTK SLLILGTASH VGKSAIVTAL CNVFSRNYRV APFKAQNMSL NSWITKDGKE
     IGIAQAIQAK AAGVEPTADM NPILLKPKGD RQSQVIILGE PYADKTAGEY YDSIEDTHEI
     LKGSLDRLSD EYEIIVMEGA GGAAEINLYE RDVVNIGTAR ATNAPIILVG DIERGGVFAS
     LYGTIELLPE DVRKRVSGFI INKFRGDPEI LNPGLEELEK RTGIPVLGVL PFSSINIPSE
     DSVSINDKSN NNDSSNDVEI AIIRLPRISN FTDFEPLEKL AKVNYVDLED NLGNPDAVII
     PGTKNTISDF VDLRESGMYD QIKKLHGKIP IIGICGGYQM LGTKIHDSGV EGEQKAEYEG
     LGLLDIETIF DAYKKTTVQT TKTITCGGPL LEPIKGEKIS GYEIHMGDTT SQNFVFDDDG
     CMDDTGLVFG TYLHGLFENE NIRNSFVRYL CEKKGLEFKP QKIISQQEAY NMLGDMVSDG
     LDMEKLYDIL GIGSGKV
//

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