(data stored in SCRATCH3701 zone)

HOGENOM6: METFK_1_PE1685

ID   METFK_1_PE1685                       STANDARD;      PRT;   864 AA.
AC   METFK_1_PE1685; Q1H0N1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (METFK_1.PE1685).
GN   OrderedLocusNames=Mfla_1688;
OS   METHYLOBACILLUS FLAGELLATUS KT.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Methylophilales;
OC   Methylophilaceae; Methylobacillus.
OX   NCBI_TaxID=265072;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS METFK_1.PE1685.
CC       Methylobacillus flagellatus KT, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:Q1H0N1_METFK
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q1H0N1; -.
DR   EMBL; CP000284; ABE49956.1; -; Genomic_DNA.
DR   RefSeq; YP_545797.1; NC_007947.1.
DR   ProteinModelPortal; Q1H0N1; -.
DR   SMR; Q1H0N1; 42-533, 547-854.
DR   STRING; Q1H0N1; -.
DR   GeneID; 4000943; -.
DR   GenomeReviews; CP000284_GR; Mfla_1688.
DR   KEGG; mfa:Mfla_1688; -.
DR   NMPDR; fig|265072.7.peg.1712; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; Q1H0N1; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; METFK_1.PE1685; -.
DR   PRODOM; METFK_1_PE1685.
DR   SWISS-2DPAGE; METFK_1_PE1685.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   864 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MALSHLKADS KIMDQFAKET LPISLEDEMR RSYLDYAMSV IVGRALPDVR DGLKPVHRRV
     LFAMHELNND WNRPYKKSAR IVGDVIGKYH PHGDTAVYDT IVRMAQDFSL RYMLVDGQGN
     FGSVDGDNAA AMRYTEIRMA RIAHELLADI DKETVDFGPN YDGSEHEPLI MPARIPNLLI
     NGSSGIAVGM ATNIPPHNLN EVIAACLALL KNPETTVDEL IEIIPAPDFP TAGIIYGTVG
     VREGYRTGRG RVVMRGRTHV EDLEKGNRQA LIVDELPYQV NKKTFVEKIA ELVNEKKIEG
     ISDLRDESDK SGMRVVIELK RGEVPEVVLN NLYKQTQLQD TFGMNMVALL DGQPRLLNLK
     QMLEAFLRHR REVVTRRTVY ELRKARERGH VLEGLAVALA NVDEMIALIK AAPTPPEAKR
     ELMARTWKSP VVEEMLKRAA MEASRPEGLA VNFGLTPDGY KLSDVQAQEI LQMRLQRLTG
     LEQDKIVNEY KEIMDVIADL LDILARSERV TQIIVEELTA ILNQFGDKRR SEIVHNAQDL
     SLEDLITPQD VVVTLSHTGY VKSQPLEEYR AQRRGGRGKQ AAATKEDDFI DKMFVANTHD
     YILCFSSRGR VYWLKVYEVP QGSRVSRGKP IVNLFPLEDG EKINAILPVK EFDENHFVFM
     ATAKGTVKKT ALTEFSNPRR SGIIALNLDD GDYLIGAEVT NGVNDIVLVS NGGKAVWFDE
     EDVRPMGRAA RGVRGMKLQG KQQVISLLIA DNDKQTVLVA TENGYGKRTV LADFRHSGRG
     TQGVKAIATS ERNGIVVGAR LVGDDDEIML ITTGGVLIRT RVKEIRELGR ATQGVTLINL
     GEGEKLSGLE KVVETDDDNE AVDE
//

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