(data stored in SCRATCH3701 zone)

HOGENOM6: METPP_1_PE2232

ID   METPP_1_PE2232                       STANDARD;      PRT;   873 AA.
AC   METPP_1_PE2232; A2SI05;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; EC=5.99.1 3; (METPP_1.PE2232).
GN   OrderedLocusNames=Mpe_A2238;
OS   METHYLIBIUM PETROLEIPHILUM PM1.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Methylibium.
OX   NCBI_TaxID=420662;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS METPP_1.PE2232.
CC       Methylibium petroleiphilum PM1 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:A2SI05_METPP
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; A2SI05; -.
DR   EMBL; CP000555; ABM95194.1; -; Genomic_DNA.
DR   RefSeq; YP_001021429.1; NC_008825.1.
DR   ProteinModelPortal; A2SI05; -.
DR   SMR; A2SI05; 30-524, 546-857.
DR   STRING; A2SI05; -.
DR   GeneID; 4785370; -.
DR   GenomeReviews; CP000555_GR; Mpe_A2238.
DR   KEGG; mpt:Mpe_A2238; -.
DR   NMPDR; fig|279263.3.peg.1705; -.
DR   eggNOG; COG0188; -.
DR   OMA; TGRGRIY; -.
DR   PhylomeDB; A2SI05; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; METPP_1.PE2232; -.
DR   PRODOM; METPP_1_PE2232.
DR   SWISS-2DPAGE; METPP_1_PE2232.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   873 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTQFAKETLP ISLEEEMRRS YLDYAMSVIV GRALPDARDG LKPVHRRVLF AMHELNNDWN
     RPYKKSARIV GDVIGKYHPH GDTAVYDTIV RMAQDFSLRH MLVDGQGNFG SVDGDNAAAM
     RYTEIRLSKI AHEMLADLDK GTVDFGPNYD GSEKEPLVMP TRLPNLLVNG SAGIAVGMAT
     NIPPHNLNET VDACLHLLKN PEASIDELME IIPAPDFPTA GIIYGLNGVR EGYRTGRGKV
     VMRAKCHFED IDKGARQSII VDEIPYQVNK KTLLERMAEL VHEKKLEGIS HIQDESDKSG
     MRVVIELKRG EVPEVVLNNL YKQTQLQDSF GINMVALVDG QPKLCNLRDL VEVFLEHRRE
     VVTRRTVFEL RKARERGHVL EGLAVALANI DEFIEIIKNS PTPPLAKQGL MDKSWDSSLV
     REMLVRAASD TPGGRDAFRP EGLPAVYGMQ ADGLYRLSDD QAQEILQMRL QRLTGLEQDK
     IIGEYKEVMA HIADLLDILS KPERVTTIIG EELVAVKQEF GQTKLGARRS VIEHNVQELG
     TEDLITPTDM VVTLSHTGYV KSQPLAEYRA QRRGGRGKQA TQTKDDDWIE QLFIANTHDW
     MLCFSNRGRV YWLKVWEVPQ GGRAARGKPI VNMFPLQPNE KITVVLPLTG EFRTFPSDHY
     IFMSTALGTV KKTALDEFSN PRKAGIIAVD LDEGDHLIGA ALTDGKHDVM LFSDGGKAVR
     FDEDDVRPMG RNARGVRGMA LEPGQNVIAM LVAEDESQSV LTATENGYGK RTSITEYTRH
     GRGTKGMIAI QQTERNGRVV AATLVRPEDE IMLITDRGVL VRTRVSEIRE LGRATQGVTL
     ISLDDGSQLG GLQRIVENDA GSDAGDTEET PAP
//

If you have problems or comments...

PBIL Back to PBIL home page