(data stored in SCRATCH3701 zone)

HOGENOM6: METS6_1_PE1556

ID   METS6_1_PE1556                       STANDARD;      PRT;   848 AA.
AC   METS6_1_PE1556; E4QI37;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; (METS6_1.PE1556).
GN   Name=gyrA; OrderedLocusNames=MPQ_1600;
OS   METHYLOVORUS SP. MP688.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Methylophilales;
OC   Methylophilaceae; Methylovorus.
OX   NCBI_TaxID=887061;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS METS6_1.PE1556.
CC       Methylovorus sp. MP688 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:E4QI37_METS6
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; E4QI37; -.
DR   EMBL; CP002252; ADQ84755.1; -; Genomic_DNA.
DR   RefSeq; YP_004039991.1; NC_014733.1.
DR   GeneID; 9996438; -.
DR   GenomeReviews; CP002252_GR; MPQ_1600.
DR   KEGG; mep:MPQ_1600; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; METS6_1.PE1556; -.
DR   PRODOM; METS6_1_PE1556.
DR   SWISS-2DPAGE; METS6_1_PE1556.
KW   DNA gyrase, a subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   848 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MDQFAKETLP ISLEDEMRRS YLDYAMSVIV GRALPDVRDG LKPVHRRVLF AMHELSNDWN
     RPYKKSARIV GDVIGKYHPH GDTAVYDTIV RMAQDFSLRY MLVDGQGNFG SVDGDNAAAM
     RYTEIRMAKI AHELLADIDK ETVDFGPNYD GSEHEPLIMP ARIPNLLING SSGIAVGMAT
     NIPPHNLNEV VDACLVLLKN PETTVDELID IIPAPDFPTA GIIYGTLGVK EGYRTGRGRV
     VMRGRTHVED MEKGNRQALI IDELPYQVNK KTLIEKIAEL VNDKKIEGIS DLRDESDKSG
     MRVVIELKRG EVPEVILNNL YKQTQLQDTF GMNMVALLDG QPRLLNLKQM LEAFLRHRRE
     VITRRTVYEL RKARERGHVL EGLAVALANV DEMIALIKAA PTPPEAKKSL MARTWVSPVV
     EEMLKRAAME ASRPDGLSVD FGMTPNGYRL SDVQAQEILQ MRLQRLTGLE QDKIVNEYKE
     VMDVIADLLD ILAKPERVTQ MIVDELAAIR QQFGDERRSE IVHNAQDLSL EDLITPQDVV
     VTLSHTGYVK SQPLDEYRAQ RRGGRGKQAT ATKEDDFIDK MFVANTHDYI LCFSSRGRVY
     WLKVYEVPQG SRISRGKPIV NLFPLEDGEK INAILPVKEF DENHFIFMAT AQGTVKKTAL
     VEFSNPRRAG IIAINLDDGD YLIGAEVTNG ANDIVLVSNG GKAVWFDEED VRAMGRNTRG
     VRGMKLMAKQ RVISLLIAED DKQTVLVATE NGYGKRTVLS DFRHSGRGTQ GVKAIATSER
     NGSVVAARLV SDEDEIMLIT TGGVLIRTRV KEIRELGRAT QGVTLINLGE NEKLSGLEKV
     VETDDADE
//

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