(data stored in SCRATCH3701 zone)

HOGENOM6: METSB_1_PE2181

ID   METSB_1_PE2181                       STANDARD;      PRT;   927 AA.
AC   METSB_1_PE2181; B8ET28;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase, A subunit; EC=5.99.1 3; (METSB_1.PE2181).
GN   OrderedLocusNames=Msil_2232;
OS   METHYLOCELLA SILVESTRIS BL2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Beijerinckiaceae; Methylocella.
OX   NCBI_TaxID=395965;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS METSB_1.PE2181.
CC       Methylocella silvestris BL2 chromosome, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:B8ET28_METSB
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; B8ET28; -.
DR   EMBL; CP001280; ACK51166.1; -; Genomic_DNA.
DR   RefSeq; YP_002362528.1; NC_011666.1.
DR   ProteinModelPortal; B8ET28; -.
DR   SMR; B8ET28; 38-520.
DR   STRING; B8ET28; -.
DR   GeneID; 7091354; -.
DR   GenomeReviews; CP001280_GR; Msil_2232.
DR   KEGG; msl:Msil_2232; -.
DR   OMA; TGRGRIY; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; METSB_1.PE2181; -.
DR   PRODOM; METSB_1_PE2181.
DR   SWISS-2DPAGE; METSB_1_PE2181.
KW   DNA gyrase, A subunit;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   927 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADNDDTGPG APGSDIRPVS ISDEMRRSYL DYAMSVIVSR ALPDVRDGLK PVHRRILFSM
     HEQNHTPDRP YVKCARIVGD VMGKYHPHGD SAIYDALVRM AQGFSMRLPL IDGQGNFGSV
     DGDPPAAMRY TESRLARPAM ALLEDIDSDT VDFQDNYDGK EREPVVLPAR FPNLLVNGAG
     GIAVGMATNI PPHNLGEVID AVIALIDNPE LTIEELMAYV PGPDFPTGGA ILGRTGIQSA
     YLTGRGSVLT RAKVEVETLR KEREALIVTE IPYQINKSSL VEKIADLVRE KRVEGISDLR
     DESDRDGMRI VIELKRDAVA EVVLNQLWRY TALQSSFACN MIALNGGRPE MLTLKDFLTA
     FVDFREEVVT RRTKYLLGKA RDAAHLQVGL AIAVANIDEV IRLIRSSADA AAAREALMAR
     SWPAHDMAPL VLLIADPRHI LSENGECRLS EAQARAILEL RLQRLTALGR EEIAEALNKL
     AVEIADYLEI LHSRERLFSI VKEEMLAVKA AHATPRRTII LDSATGVDDE DLIQREDMVV
     TVSHHGYVKR VPLATYRAQR RGGKGRSAMQ TRDEDFVARL FVASTHAPVL FFSSAGQVYK
     EKVWRLPLAA PQARGKALVN MLPLEQGERI TTIMPLPEEE DAWATLDVMF ATTRGTVRRN
     KLSDFAQVNR AGKIAMRIDE GEEIVDVQIC GEDADVLLTT AKGQCIRFPV TDVRVFKGRD
     SMGVRGISLS EGDRVISLAI LRHTEADSGE RIAYLKMRRA VAGEASAEAG AESPADAQGE
     DGAEDAGPQS LSPDRYARMS ADEQIILTLS SNGYGKRTSS YEYRITGRGG KGIVAMVVNP
     RNGLLVASMP VEDGDEIMLV TNGGQLIRCP VEGIRVAGRG TQGVIVFNTG ADEQVVSVER
     ITEEDAARGE TEEGEPSSDP STEPGEA
//

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