(data stored in SCRATCH3701 zone)

HOGENOM6: MICLC_1_PE6

ID   MICLC_1_PE6                          STANDARD;      PRT;   898 AA.
AC   MICLC_1_PE6; C5C7X9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA gyrase subunit A; (MICLC_1.PE6).
GN   OrderedLocusNames=Mlut_00060;
OS   MICROCOCCUS LUTEUS NCTC 2665.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Micrococcineae; Micrococcaceae; Micrococcus.
OX   NCBI_TaxID=465515;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MICLC_1.PE6.
CC       Micrococcus luteus NCTC 2665, complete genome.
CC       sequence.
CC   -!- ANNOTATIONS ORIGIN:C5C7X9_MICLC
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; C5C7X9; -.
DR   EMBL; CP001628; ACS29581.1; -; Genomic_DNA.
DR   RefSeq; YP_002956135.1; NC_012803.1.
DR   ProteinModelPortal; C5C7X9; -.
DR   STRING; C5C7X9; -.
DR   GeneID; 7985565; -.
DR   GenomeReviews; CP001628_GR; Mlut_00060.
DR   KEGG; mlu:Mlut_00060; -.
DR   ProtClustDB; PRK05560; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; MICLC_1.PE6; -.
DR   PRODOM; MICLC_1_PE6.
DR   SWISS-2DPAGE; MICLC_1_PE6.
KW   DNA gyrase subunit A;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   898 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDETTPQTP DEPVEGAPIP GTPQTGLDIE VEHYVLPEGA ADKVEPVDLE SEMKRSYLDY
     AMAVIVGRAL PDVRDGLKPV HRRVLYAMYD GGYRPDRAFN KSARVVGDVM GNYHPHGDTA
     IYDALVRLIQ DWVQRYPLAL GQGNFGSPGN DGAAAQRYTE TKMAPLAMEM VRDIDEDTVD
     MQDNYDGKQQ EPVVLPARYP NLLVNGSSGI AVGMATNIPP HNMREVAAGV QWYLEHPEAT
     REELLEALLA RVHGPDFPTG AQILGRKGIE EVYRTGRGPI TMRAVVNVEE IQGRTCLVVT
     ELPYMTNPDN LAAKIAEMVR DGKISGIADM RDETSGRTGQ RLVIVLKRDA VAKVVLNNLY
     KHTELQSNFS ANMLALVDGV PRTLSLDGFV HHWVKHQIDV IVRRTAFRKR KAEERAHILR
     GLLKALDMLD EVIATIRRSA SADVAREALK ELLDIDDVQA QAILQMQLRQ LAALESQKIQ
     DEYDDLMAKI AEYNRILESP QRQREVISEE LAEIVAKHGD DRRTEIMAGF DGDMSIEDLI
     PEEEMVVSIT RGGYVKRTRI DQYRSQARGG KGVRGATLRG DDVVEHFLTV STHHWLLFFT
     NFGRVYRIKT YELLEAGRDA KGQHVANLLA FQPDERIAQI QPLVDYGRAP YLVLATRGGL
     VKKTPLLDYD TNRTAGLIAI KLREGDELVS ARVVSPDDDL ILISHKGQSL RFTATDEALR
     PMGRATSGVT GMKFRDDDSL LTMDVVEEDG YVFTVTDGGF AKRTHVDEYR LQNRGGLGIK
     VAKLVDDRGE LAGGLVVRED QEVLVVMASG KVVRSAVAGV PAKGRDTMGV IFAKPDKRDR
     IVAVTLNNEQ EMEAKADAEA EAGPDVPLDA DIDPTDPVAA PEDALTQDAG EGADGGEQ
//

If you have problems or comments...

PBIL Back to PBIL home page