(data stored in SCRATCH3701 zone)

HOGENOM6: MOBCV_1_PE684

ID   MOBCV_1_PE684                        STANDARD;      PRT;   847 AA.
AC   MOBCV_1_PE684; D6ZJV4;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   SubName: Full=DNA topoisomerase (MOBCV_1.PE684) (ATP-hydrolyzing);
DE   EC=5.99.1 3; .
GN   Name=gyrAS; OrderedLocusNames=HMPREF0573_10684;
OS   MOBILUNCUS CURTISII ATCC 43063.
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Actinomycineae; Actinomycetaceae; Mobiluncus/Falcivibrio group;
OC   Mobiluncus.
OX   NCBI_TaxID=548479;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOBCV_1.PE684.
CC       Mobiluncus curtisii ATCC 43063 chromosome, complete genome.
CC       1..405839 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:D6ZJV4_MOBCV
CC   -!- FUNCTION: DNA gyrase negatively supercoils closed circular double-
CC       stranded DNA in an ATP-dependent manner and also catalyzes the
CC       interconversion of other topological isomers of double-stranded
CC       DNA rings, including catenanes and knotted rings (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP-dependent breakage, passage and rejoining
CC       of double-stranded DNA.
CC   -!- SUBUNIT: Made up of two chains. The A chain is responsible for DNA
CC       breakage and rejoining; the B chain catalyzes ATP hydrolysis. The
CC       enzyme forms an A2B2 tetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- GENE_FAMILY: HOG000076278 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; D6ZJV4; -.
DR   EMBL; CP001992; ADI67003.1; -; Genomic_DNA.
DR   RefSeq; YP_003718497.1; NC_014246.1.
DR   GeneID; 9336345; -.
DR   GenomeReviews; CP001992_GR; HMPREF0573_10684.
DR   KEGG; mcu:HMPREF0573_10684; -.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   InterPro; IPR020899; Arg_repress_C.
DR   InterPro; IPR005743; GyrA.
DR   InterPro; IPR006691; GyrA/parC_pinwhl.
DR   InterPro; IPR002205; Topo_IIA_A/C.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a.
DR   InterPro; IPR013760; Topo_IIA_cen.
DR   Gene3D; G3DSA:3.30.1360.40; Arg_repress; 1.
DR   Gene3D; G3DSA:3.90.199.10; Topo_IIA_A/C_ab; 1.
DR   Gene3D; G3DSA:1.10.268.10; Topo_IIA_A_a; 1.
DR   Pfam; PF03989; DNA_gyraseA_C; 6.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Topo_IIA_cen; 1.
DR   TIGRFAMs; TIGR01063; GyrA; 1.
DR   HOGENOMDNA; MOBCV_1.PE684; -.
DR   PRODOM; MOBCV_1_PE684.
DR   SWISS-2DPAGE; MOBCV_1_PE684.
KW   ATP-binding; Complete proteome; Cytoplasm; DNA-binding; Isomerase;
KW   Nucleotide-binding; Topoisomerase.
SQ   SEQUENCE   847 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MADNQDNNDS EVEEIIHSDA PVITEAESTR VMQVDLEKEM KKSYMDYAMS VIVGRALPDV
     RDGLKPVHRR VIYTMYDGGY RPNGGYSKCM RVVGDVLGHF HPHGDSSVYD ALARLVQPWS
     MRYPLVAGQG NFGSPGNLGP AAPRYTECKM ATLAMEMVRD IDEDTVDFMD NYDGRSQEPT
     VLPSRIPNLL INGSEGIAVG MATRIPPHNL REVADAAQWY LQNPEATREE LLAACLQRIK
     GPDFPTGATI LGRRGIEETY RTGRGSITQR AVVNVEELNG RTCLVATELP YQVNPDNLQV
     KIAQLVKDGQ LQGIADIRDE TSDRAGTRIV VVLKRDAVPK VVLNNLYKRT QLQDSFPANM
     LALVDGVPRT LSIDGFIHYW IAHQVDVIKR RTAFRLAKAQ ERLHILQGYL AALDALDEVI
     ALIRRSPTAE DARVGLMDFL KVDEVQADAI LALQLRRLAA LERQKILDEH AELEAKVADF
     KDILARPERQ RSIVSEELGE ITDKWGDERK TTIVPFDGEM SMEDLIPEED VVVTITRGGY
     AKRTRVDAYR SQHRGGKGIK GASLREEDQV EHFFTTSSHD WLLFFTNFGR VYRAKAYEIP
     EGGRDSKGQH VANLLAFQPD ERIAQVLQVS SFADKDYLVL ATRLGFVKKT RLTDYDTNRT
     GGLIAIKLRE DSAGEADQLV SACLADATDD LILVSRHGQS LRFNACDEQL RPMGRATSGV
     TGMRFRADDE LLTMDVVRPE ADLFVVTEGG YAKRTALSEY RVQGRGGLGI KVANLVEARG
     DLVGALVTEE DSEVLVIMAG GKIVRSRVDE VSRTGRNTQG VIFSRADEGD KVIAITLNVD
     NDPQLED
//

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