(data stored in ACNUC7421 zone)

HOGENOM: MOOTA_1_PE1000

ID   MOOTA_1_PE1000                       STANDARD;      PRT;   437 AA.
AC   MOOTA_1_PE1000; Q2RJP8;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName:
DE   Full=Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO;
DE   EC=2.1.1 74;AltName: Full=Folate-dependent tRNA (MOOTA_1.PE1000)
DE   (uracil-5-)-methyltransferase;AltName: Full=Folate-dependent
DE   tRNA(M-5-U54)-methyltransferase; .
GN   Name=trmFO; Synonyms=gid; OrderedLocusNames=Moth_1027;
OS   MOORELLA THERMOACETICA ATCC 39073.
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Moorella group; Moorella.
OX   NCBI_TaxID=264732;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOOTA_1.PE1000.
CC       Moorella thermoacetica ATCC 39073, complete genome.
CC       7874984..8874983 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:TRMFO_MOOTA
CC   -!- FUNCTION: Catalyzes the folate-dependent formation of 5-methyl-
CC       uridine at position 54 (M-5-U54) in all tRNAs (By similarity).
CC   -!- CATALYTIC ACTIVITY: 5,10-methylenetetrahydrofolate + tRNA
CC       containing uridine at position 54 + FADH(2) = tetrahydrofolate +
CC       tRNA containing ribothymidine at position 54 + FAD.
CC   -!- COFACTOR: FAD (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the MnmG family. TrmFO subfamily.
CC   -!- GENE_FAMILY: HOG000252054 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2RJP8; -.
DR   EMBL; CP000232; ABC19341.1; -; Genomic_DNA.
DR   RefSeq; YP_429884.1; NC_007644.1.
DR   ProteinModelPortal; Q2RJP8; -.
DR   STRING; Q2RJP8; -.
DR   GeneID; 3832647; -.
DR   GenomeReviews; CP000232_GR; Moth_1027.
DR   KEGG; mta:Moth_1027; -.
DR   NMPDR; fig|264732.9.peg.1009; -.
DR   eggNOG; COG1206; -.
DR   OMA; RFAGQIT; -.
DR   ProtClustDB; PRK05335; -.
DR   BioCyc; MTHE264732:MOTH_1027-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0047151; F:methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity; IEA:EC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   HAMAP; MF_01037; TrmFO; 1; -.
DR   InterPro; IPR004417; Folate-dep_Ribothymidyl_synth.
DR   InterPro; IPR002218; GIDA-rel.
DR   Pfam; PF01134; GIDA; 1.
DR   TIGRFAMs; TIGR00137; Gid_trmFO; 1.
DR   PROSITE; PS01280; GIDA_1; FALSE_NEG.
DR   PROSITE; PS01281; GIDA_2; FALSE_NEG.
DR   HOGENOMDNA; MOOTA_1.PE1000; -.
KW   tRNA (uracil-5-)-methyltransferase Gid;
KW   Complete proteome; Cytoplasm; FAD; Flavoprotein; Methyltransferase;
KW   Reference proteome; Transferase; tRNA processing.
SQ   SEQUENCE   437 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSDKVIIIGG GLAGSEAAWQ AARRGMKVEL WEMRPGKLTP AHSTGYLAEL VCSNSLRADS
     LENAAGLLKA EMRQAGSLIM EVAAACRVPA GKALAVDREE FASRVTAILE AHPGITVIRE
     EVQAIPDNGP VIIATGPLTS PAMVRALKEF TGAEYLYFYD AAAPIVTAES LDYSRIFKGS
     RYGRGEDDYL NCPLNKEEYE AFYQALVTAE RHPRHEFEPE VVFEGCMPVE VMAARGPDTL
     RFGPMRPVGL IDPATGREPY AVVQLRQDNA AGTLYNLVGF QTSLKWGEQE RVFRLIPGLR
     EAEFVRFGVM HRNTYVNSPR LLQPTLQVKG YPWLFLAGQL TGVEGYIESA ACGLVAGVNA
     TRFARGEEPL IPPPATAHGA LLHYITDPTH TPFQPMHINY GLLPPLEHRV KNRVERNRIL
     AARALEIWNS SGEFSGN
//

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