(data stored in ACNUC7421 zone)

HOGENOM: MOOTA_1_PE1007

ID   MOOTA_1_PE1007                       STANDARD;      PRT;   240 AA.
AC   MOOTA_1_PE1007; Q2RJP1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Uridylate kinase; Short=UK; EC=2.7.4 22;AltName:
DE   Full=Uridine monophosphate kinase; Short=UMP kinase; Short=UMPK;
DE   (MOOTA_1.PE1007).
GN   Name=pyrH; OrderedLocusNames=Moth_1034;
OS   MOORELLA THERMOACETICA ATCC 39073.
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Moorella group; Moorella.
OX   NCBI_TaxID=264732;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOOTA_1.PE1007.
CC       Moorella thermoacetica ATCC 39073, complete genome.
CC       7874984..8874983 annotated by Ensembl
CC   -!- ANNOTATIONS ORIGIN:PYRH_MOOTA
CC   -!- FUNCTION: Catalyzes the reversible phosphorylation of UMP to UDP
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + UMP = ADP + UDP.
CC   -!- ENZYME REGULATION: Allosterically activated by GTP. Inhibited by
CC       UTP (By similarity).
CC   -!- PATHWAY: Pyrimidine metabolism; CTP biosynthesis via de novo
CC       pathway; UDP from UMP (UMPK route): step 1/1.
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the UMP kinase family.
CC   -!- GENE_FAMILY: HOG000047187 [ FAMILY / ALN / TREE ]
DR   UniProtKB/Swiss-Prot; Q2RJP1; -.
DR   EMBL; CP000232; ABC19348.1; -; Genomic_DNA.
DR   RefSeq; YP_429891.1; NC_007644.1.
DR   HSSP; P65938; 1Z9D.
DR   ProteinModelPortal; Q2RJP1; -.
DR   SMR; Q2RJP1; 3-236.
DR   STRING; Q2RJP1; -.
DR   GeneID; 3832654; -.
DR   GenomeReviews; CP000232_GR; Moth_1034.
DR   KEGG; mta:Moth_1034; -.
DR   NMPDR; fig|264732.9.peg.1016; -.
DR   eggNOG; COG0528; -.
DR   OMA; RHMEKGR; -.
DR   BioCyc; MTHE264732:MOTH_1034-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0033862; F:UMP kinase activity; IEA:EC.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01220_B; PyrH_B; 1; -.
DR   InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR   InterPro; IPR011817; Uridylate_kinase.
DR   InterPro; IPR015963; Uridylate_kinase_bac.
DR   Gene3D; G3DSA:3.40.1160.10; Aa_kinase; 1.
DR   Pfam; PF00696; AA_kinase; 1.
DR   PIRSF; PIRSF005650; Uridylate_kin; 1.
DR   SUPFAM; SSF53633; Aa_kinase; 1.
DR   TIGRFAMs; TIGR02075; PyrH_bact; 1.
DR   HOGENOMDNA; MOOTA_1.PE1007; -.
KW   uridylate kinase;
KW   Allosteric enzyme; ATP-binding; Complete proteome; Cytoplasm; Kinase;
KW   Nucleotide-binding; Pyrimidine biosynthesis; Reference proteome;
KW   Transferase.
SQ   SEQUENCE   240 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGQPKYKRVI LKISGEALAG NQGFGIDQEV ITSIASQIKE VRELGVDVAI VVGGGNIWRG
     VKGSARGMDR ATADYMGMLA TVINSLALQD ALENQGVDTR VQTAIEMRQI AEPYIRRRAI
     RHLEKGRVVI FAAGTGNPYF STDTTAALRA AELEADVILM AKRVDGVYDS DPEINPEAKR
     LKDLDYLTVL NGGLGVMDST ATSLCMDNHI PIIVFGIKEK GNILKAILGE PIGTYVGRLE
//

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