(data stored in ACNUC15234 zone)

HOGENOM: MOUSE11_PE263

ID   MOUSE11_PE263                        STANDARD;      PRT;   1504 AA.
AC   MOUSE11_PE263; Q5SWP3; Q6I6F5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=NAC-alpha domain-containing protein 1; (MOUSE11.PE263).
GN   Name=Nacad; Synonyms=Kiaa0363;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE11.PE263.
CC       Mus musculus chromosome 11 NCBIM37  sequence 1..121843856 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:NACAD_MOUSE
CC   -!- FUNCTION: May prevent inappropriate targeting of non-secretory
CC       polypeptides to the endoplasmic reticulum (ER). May bind to
CC       nascent polypeptide chains as they emerge from the ribosome and
CC       block their interaction with the signal recognition particle
CC       (SRP), which normally targets nascent secretory peptides to the
CC       ER. May also reduce the inherent affinity of ribosomes for protein
CC       translocation sites in the ER membrane (M sites) (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the NAC-alpha family.
CC   -!- SIMILARITY: Contains 1 NAC-A/B (NAC-alpha/beta) domain.
CC   -!- GENE_FAMILY: HOG000113723 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000041073;ENSMUST00000045713;ENSMUSP00000049490.
DR   EMBL; AB182283; - ;
DR   EMBL; AL603787; - ;
DR   EMBL; BC072589; - ;
DR   UniProtKB/Swiss-Prot; Q5SWP3; Q6I6F5; -.
DR   EMBL; AL603787; CAI24213.1; -; Genomic_DNA.
DR   EMBL; BC072589; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AB182283; BAD23961.1; -; mRNA.
DR   IPI; IPI00112419; -.
DR   RefSeq; NP_001075121.1; NM_001081652.1.
DR   UniGene; Mm.337771; -.
DR   ProteinModelPortal; Q5SWP3; -.
DR   SMR; Q5SWP3; 1363-1502.
DR   PhosphoSite; Q5SWP3; -.
DR   PRIDE; Q5SWP3; -.
DR   Ensembl; ENSMUST00000045713; ENSMUSP00000049490; ENSMUSG00000041073.
DR   GeneID; 192950; -.
DR   KEGG; mmu:192950; -.
DR   UCSC; uc007hyy.1; mouse.
DR   CTD; 23148; -.
DR   MGI; MGI:3603030; Nacad.
DR   eggNOG; roNOG09734; -.
DR   GeneTree; ENSGT00440000033468; -.
DR   InParanoid; Q5SWP3; -.
DR   OMA; EAPECPE; -.
DR   OrthoDB; EOG4DJJXZ; -.
DR   PhylomeDB; Q5SWP3; -.
DR   NextBio; 371390; -.
DR   ArrayExpress; Q5SWP3; -.
DR   Bgee; Q5SWP3; -.
DR   Genevestigator; Q5SWP3; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR002715; Nas_poly-pep-assoc_cplx.
DR   Pfam; PF01849; NAC; 1.
DR   PROSITE; PS51151; NAC_AB; 1.
DR   HOGENOMDNA; MOUSE11.PE263; -.
KW   ENSMUSG000000410735old_1320000031; ENSMUSP000000494901old_1320000031;
KW   AB182283; AL603787; BC072589;
KW   Complete proteome; Cytoplasm; Nucleus; Phosphoprotein;
KW   Protein transport; Reference proteome; Transport.
SQ   SEQUENCE   1504 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSALPLALRS ARRAGARSLG LIGGRGSADV IYAPPPPSRG AVAVLATPSA LTDRGTERQG
     YRQAHVQAMP GEAAGAELPL PEAGGPGSRT DHSCDAAIAT ILKGDQLEPH GLTPGPSPLA
     LTFLSSKPGA RPQPEGASWD AGPSGAASAW VDPAEGSPSL VVLPEGLPLR PVPAEGPLPT
     TLEPRIVMGE ETCQVIASPR AAWPVLRDRE GGHPALHPPP ELCSQGDPPV PSPPPDLESY
     FTPPSTPTKS THALLPDHGP HRDAWDLEAE LLDELLDSTP ASPSGSYITA DGDSWASSPS
     CSLSLLDPAE GLDFPSDWGL SPSGSVADDL EPHPAAPPEP PSSESSLSAD SSSSWSQEGH
     FFDPNFLAND PMIPAALLPF RGSLIFQVEA VEVTPLPQEE EEDEEDVAAT AAAAAPAAAT
     PDGDLAGEGE DDSTSASFLQ SLSDLSIIEG MDEAFAFRDD TSAASSDSDS ASYAGADDDR
     LYSGEPHAQP SAQNTEQAYR SRATFPGIES TPQTSEQEIC LTNSQESVAE IAEEILTLGL
     ESEAMRTPPD QQAAPGPQVE ETPTVTPWVG NKVDLVVEQV SKALPEPCQE GISTTLGCKP
     LTAEAIPDLQ EGASPSLCPV LPEKKEEGQG LPSTLEYVAV ALEGPWKAEG GVTIPQDPLM
     TLPPLLQSTV PTSGPESVAV VALEPQQNEG CVTVLPDVPV VLPPSPQSVD PSSGPEAMAV
     ATYEFQRAKE GTPGLQDSPV AASPALQGPD PTSEPEPEVV VTSRSQQDEG IVTVPQESPT
     ASSLTLQSSH PTSDQEREVA ATLGPQQAEE GVTIPQVAPV ASPSLLQGLE STSDLESVVV
     GTPESQQDEG IATATQDTPV MAPPPLRGTD STSDPELIAP DTSQALQREA GHTPGTKPSV
     SEAHQELGVA SGPRPVPKEG DAEPPPHSAP PASNQAQQNG SEPGYKSDSF GAPEESDSTL
     STKTSEPTSC MGEKVAANMS APKQGACLEA HDGVKTHSPQ REALRSKNKR GRGTKSPGQG
     NGPKSATSQG AVETCRAHSA ARSEVSQPQL RSNEDTSGPR LPVAVSVQAR LGSCPGSPAR
     ATCTLSRVYA EETSRCAPPF QHLEPMLGLG SAEQPKVTPG ILNLSPDNSA GDLLTTSQNR
     FLDPDPAPST LDRASQSSPG PPDPCLCPPP QKASEEEEKP PASRGPMPRA GAQGAAAITT
     SGSTKPPGAR QRVSLSPHST LNPKVAPTDT KDLACIISSP CQVPPPSGTQ NPSGPREFPA
     LEQKDEDSLE EDAQRAPGSG QRWESHGESS SELDEYLAPP PDAQRTPGSG QRSESHGESS
     SELGEQDLSP QKSQCPAQGP AGSNEETIAK AKQSRSEKKA RKAMSKLGLR QIQGVTRITI
     QKSKNILFVI AKPDVFKSPA SDTYVVFGEA KIEDLSQQVH KAAAEKFKVP SEPSALVPEL
     SPGPRVRPEC EEQEEEDEEV EEAGLEPRDI ELVMAQANVT RAKAVRALKD NHSDIVNAIM
     ELTM
//

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