(data stored in ACNUC7421 zone)

HOGENOM: MOUSE15_PE1349

ID   MOUSE15_PE1349                       STANDARD;      PRT;   184 AA.
AC   MOUSE15_PE1349; Q9D8T3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=GTPase RhebL1;AltName: Full=Ras homolog enriched in
DE   brain-like protein 1; Short=Rheb-like protein 1;Flags: Precursor;
DE   (MOUSE15.PE1349).
GN   Name=Rhebl1;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE15.PE1349.
CC       Mus musculus chromosome 15 NCBIM37  sequence 1..103494974 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:REBL1_MOUSE
CC   -!- FUNCTION: Binds GTP and exhibits intrinsic GTPase activity. May
CC       activate NF-kappa-B-mediated gene transcription. Promotes signal
CC       transduction through MTOR, activates RPS6KB1, and is a downstream
CC       target of the small GTPase-activating proteins TSC1 and TSC2 (By
CC       similarity).
CC   -!- SUBUNIT: Interacts with MTOR (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic
CC       side (By similarity). Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rheb family.
CC   -!- GENE_FAMILY: HOG000233973 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000023755;ENSMUST00000024518;ENSMUSP00000024518.
DR   EMBL; AK007708; - ;
DR   EMBL; AK135858; - ;
DR   EMBL; AY327413; - ;
DR   EMBL; BC016521; - ;
DR   UniProtKB/Swiss-Prot; Q9D8T3; -.
DR   EMBL; AY327413; AAP92805.1; -; mRNA.
DR   EMBL; AK007708; BAB25203.1; -; mRNA.
DR   EMBL; AK135858; BAE22699.1; -; mRNA.
DR   EMBL; BC016521; AAH16521.1; -; mRNA.
DR   IPI; IPI00111989; -.
DR   RefSeq; NP_081243.1; NM_026967.4.
DR   UniGene; Mm.259708; -.
DR   HSSP; Q15382; 1XTR.
DR   ProteinModelPortal; Q9D8T3; -.
DR   SMR; Q9D8T3; 5-170.
DR   MINT; MINT-1340904; -.
DR   STRING; Q9D8T3; -.
DR   PRIDE; Q9D8T3; -.
DR   Ensembl; ENSMUST00000024518; ENSMUSP00000024518; ENSMUSG00000023755.
DR   GeneID; 69159; -.
DR   KEGG; mmu:69159; -.
DR   UCSC; uc011zzb.1; mouse.
DR   CTD; 121268; -.
DR   MGI; MGI:1916409; Rhebl1.
DR   eggNOG; roNOG10346; -.
DR   GeneTree; ENSGT00550000074746; -.
DR   InParanoid; Q9D8T3; -.
DR   OMA; ERRCRLM; -.
DR   OrthoDB; EOG4VMFGG; -.
DR   PhylomeDB; Q9D8T3; -.
DR   NextBio; 328728; -.
DR   ArrayExpress; Q9D8T3; -.
DR   Bgee; Q9D8T3; -.
DR   CleanEx; MM_RHEBL1; -.
DR   Genevestigator; Q9D8T3; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR020849; Small_GTPase_Ras.
DR   PANTHER; PTHR24070; PTHR24070; 1.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00173; RAS; 1.
DR   TIGRFAMs; TIGR00231; Small_GTP; 1.
DR   PROSITE; PS51421; RAS; 1.
DR   HOGENOMDNA; MOUSE15.PE1349; -.
KW   ENSMUSG000000237555old_1320000031; ENSMUSP000000245181old_1320000031;
KW   AK007708; AK135858; AY327413; BC016521;
KW   Cell membrane; Complete proteome; Cytoplasm; GTP-binding; Lipoprotein;
KW   Membrane; Methylation; Nucleotide-binding; Prenylation;
KW   Reference proteome.
SQ   SEQUENCE   184 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPLVRYRKVA ILGYRSVGKT SLAHQFVEGE FLEGYDPTVE NTYSKTVTLG KDEFHLHLVD
     TAGQDEYSIL PYSLIIGVHG YVLVYSVNSL RSFQIVKNLY QKLHEGHGKT RLSVLLVGNK
     ADLSPEREVQ AVEGKKLAES WGAMFMESSA RDNQLTQDVF IKVIQEIARV ENSYGRQDRR
     CYLM
//

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