(data stored in ACNUC16162 zone)

HOGENOM: MOUSE16_PE942

ID   MOUSE16_PE942                        STANDARD;      PRT;   362 AA.
AC   MOUSE16_PE942; P54923;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=[Protein ADP-ribosylarginine] hydrolase;
DE   Short=ADP-ribosylarginine hydrolase; EC=3.2.2 19;AltName:
DE   Full=ADP-ribose-L-arginine cleaving enzyme; (MOUSE16.PE942).
GN   Name=Adprh; Synonyms=Arh1;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE16.PE942.
CC       Mus musculus chromosome 16 NCBIM37  sequence 1..98319150 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ADPRH_MOUSE
CC   -!- FUNCTION: Catalyzes the reverse reaction of mono-ADP-ribosylation.
CC   -!- CATALYTIC ACTIVITY: Protein-N(omega)-(ADP-D-ribosyl)-L-arginine +
CC       H(2)O = ADP-ribose + protein-L-arginine.
CC   -!- CATALYTIC ACTIVITY: N(omega)-(ADP-D-ribosyl)-L-arginine + H(2)O =
CC       ADP-ribose + L-arginine.
CC   -!- ENZYME REGULATION: Synergistically stimulated by magnesium and
CC       dithiothreitol (DTT) in vitro.
CC   -!- SIMILARITY: Belongs to the ADP-ribosylglycohydrolase family.
CC   -!- GENE_FAMILY: HOG000007974 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000002844;ENSMUST00000002923;ENSMUSP00000002923.
DR   EMBL; AF244347; - ;
DR   EMBL; AK003751; - ;
DR   EMBL; AK146280; - ;
DR   EMBL; AK153498; - ;
DR   EMBL; AK171798; - ;
DR   EMBL; BC003437; - ;
DR   EMBL; CH466521; - ;
DR   EMBL; L13290; - ;
DR   UniProtKB/Swiss-Prot; P54923; -.
DR   EMBL; L13290; AAA37259.1; -; mRNA.
DR   EMBL; AF244347; AAF86223.1; -; mRNA.
DR   EMBL; BC003437; AAH03437.1; -; mRNA.
DR   IPI; IPI00111149; -.
DR   PIR; A47411; A47411.
DR   RefSeq; NP_031440.1; NM_007414.3.
DR   UniGene; Mm.20047; -.
DR   ProteinModelPortal; P54923; -.
DR   SMR; P54923; 6-360.
DR   STRING; P54923; -.
DR   PhosphoSite; P54923; -.
DR   REPRODUCTION-2DPAGE; P54923; -.
DR   PRIDE; P54923; -.
DR   Ensembl; ENSMUST00000002923; ENSMUSP00000002923; ENSMUSG00000002844.
DR   GeneID; 11544; -.
DR   KEGG; mmu:11544; -.
DR   CTD; 141; -.
DR   MGI; MGI:1098234; Adprh.
DR   eggNOG; roNOG09199; -.
DR   InParanoid; P54923; -.
DR   OMA; HWSYFQD; -.
DR   OrthoDB; EOG4QJRNH; -.
DR   PhylomeDB; P54923; -.
DR   NextBio; 279014; -.
DR   ArrayExpress; P54923; -.
DR   Bgee; P54923; -.
DR   CleanEx; MM_ADPRH; -.
DR   Genevestigator; P54923; -.
DR   GermOnline; ENSMUSG00000002844; Mus musculus.
DR   GO; GO:0003875; F:ADP-ribosylarginine hydrolase activity; IMP:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051725; P:protein de-ADP-ribosylation; IEA:InterPro.
DR   InterPro; IPR012108; ADP-ribosylarg_hydro.
DR   InterPro; IPR005502; Ribosyl_crysJ1.
DR   Pfam; PF03747; ADP_ribosyl_GH; 1.
DR   PIRSF; PIRSF016939; ADP_ribslarg_hdr; 1.
DR   SUPFAM; SSF101478; Ribosyl_crysJ1; 1.
DR   HOGENOMDNA; MOUSE16.PE942; -.
KW   ENSMUSG000000028445old_1320000031; ENSMUSP000000029231old_1320000031;
KW   Q3U5N4_MOUSE; Q9CTF5_MOUSE; AF244347; AK003751; AK146280; AK153498;
KW   BC003437; CH466521; L13290;
KW   Complete proteome; Hydrolase; Magnesium; Reference proteome.
SQ   SEQUENCE   362 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MGGGLIERYV AAMVLSAAGD TLGYFNGKWE FIRDGETIHQ QLAQMGDLEA IDVARWRVSD
     DTVMHLATAE ALMEAGQSPD LPRLYSLLAK HYRDCMGDMD GRAPGGACMQ NAMLLQPNRA
     DGYRIPFNSH EGGCGAAMRA MCIGLRFPHP SQLDLLIQVS IESGRMTHHH PTGYLGSLAS
     ALFTAYAVNG KSPWQWGKGL MEVLPEAKKY ITQSGYFVKE NLQHWSYFEK EWEKYLELRG
     ILDGNSAPVF PQPFGVKERD QFYIDVSYSG WGGSSGHDAP MIAYDALLAA GDSWKELAHR
     AFFHGGDSDS TAAIAGCWWG VMYGFKGVNP ANYEKLEYRQ RLEEAGRALY SLGSKEDPVL
     DP
//

If you have problems or comments...

PBIL Back to PBIL home page