(data stored in ACNUC8465 zone)

HOGENOM: MOUSE18_PE632

ID   MOUSE18_PE632                        STANDARD;      PRT;   234 AA.
AC   MOUSE18_PE632; Q9D5U5; Q5RL33; Q9D9A0;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pseudouridine-5'-monophosphatase; Short=5'-PsiMPase;
DE   EC=3.1.3 n6;AltName: Full=Haloacid dehalogenase-like hydrolase
DE   domain-containing protein 1;AltName: Full=Haloacid dehalogenase-like
DE   hydrolase domain-containing protein 1A; (MOUSE18.PE632).
GN   Name=Hdhd1; Synonyms=Hdhd1a;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE18.PE632.
CC       Mus musculus chromosome 18 NCBIM37  sequence 1..90772031 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:HDHD1_MOUSE
CC   -!- FUNCTION: Dephosphorylates pseudouridine 5'-phosphate, a potential
CC       intermediate in rRNA degradation. Pseudouridine is then excreted
CC       intact in urine (By similarity).
CC   -!- CATALYTIC ACTIVITY: pseudouridine 5'-monophosphate + H(2)O =
CC       Pseudouridine + phosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC       CbbY/CbbZ/Gph/YieH family.
CC   -!- GENE_FAMILY: HOG000248341 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000048875;ENSMUST00000056460;ENSMUSP00000057378.
DR   EMBL; AK007231; - ;
DR   EMBL; AK014922; - ;
DR   EMBL; BC048447; - ;
DR   UniProtKB/Swiss-Prot; Q9D5U5; Q5RL33; Q9D9A0; -.
DR   EMBL; AK007231; BAB24906.1; -; mRNA.
DR   EMBL; AK014922; BAB29622.1; -; mRNA.
DR   EMBL; BC048447; AAH48447.1; -; mRNA.
DR   IPI; IPI00108475; -.
DR   RefSeq; NP_080384.2; NM_026108.3.
DR   UniGene; Mm.158150; -.
DR   ProteinModelPortal; Q9D5U5; -.
DR   SMR; Q9D5U5; 11-232.
DR   STRING; Q9D5U5; -.
DR   PhosphoSite; Q9D5U5; -.
DR   PRIDE; Q9D5U5; -.
DR   GeneID; 67365; -.
DR   KEGG; mmu:67365; -.
DR   UCSC; uc008ewy.2; mouse.
DR   CTD; 67365; -.
DR   MGI; MGI:1914615; Hdhd1a.
DR   InParanoid; Q9D5U5; -.
DR   OrthoDB; EOG46MBKM; -.
DR   NextBio; 324356; -.
DR   ArrayExpress; Q9D5U5; -.
DR   Bgee; Q9D5U5; -.
DR   Genevestigator; Q9D5U5; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IEA:EC.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005834; Dehalogen-like_hydro.
DR   InterPro; IPR023214; HAD-like_dom.
DR   InterPro; IPR006402; HAD-SF_hydro_IA_v3.
DR   Gene3D; G3DSA:3.40.50.1000; HAD-like_dom; 1.
DR   Pfam; PF00702; Hydrolase; 1.
DR   SUPFAM; SSF56784; HAD-like_dom; 1.
DR   TIGRFAMs; TIGR01509; HAD-SF-IA-v3; 1.
DR   HOGENOMDNA; MOUSE18.PE632; -.
KW   ENSMUSG000000488755old_1320000031; ENSMUSP000000573781old_1320000031;
KW   Q9D9A0_MOUSE; AK007231; AK014922; BC048447;
KW   Complete proteome; Hydrolase; Magnesium; Metal-binding;
KW   Nucleotide metabolism; Reference proteome.
SQ   SEQUENCE   234 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAAAVPVPQF RPVTHLIFDL DGLILNTEDL YTDVFEEICN RYGKKYNWDV KSLVMGKKAL
     ETAQTIVEFL NLPISKEELL KESQEKLQMV LHTAGFMPGA EELIHHLKKH RLPFALATSS
     ETVTFQTKTS RHTGFFGLFH HIVLGDDPEV KNGKPGMDIF LTCAKRFSPP PDPKDCLVFE
     DSPNGVEAAI HCGMQVVMVP HENLSADLTR KATLVLSSLH DFKPELFGLP AFTE
//

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