(data stored in ACNUC18858 zone)

HOGENOM: MOUSE19_PE714

ID   MOUSE19_PE714                        STANDARD;      PRT;   428 AA.
AC   MOUSE19_PE714; Q09324; O35981; Q8BRB2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein
DE   beta-1,6-N-acetylglucosaminyltransferase; EC=2.4.1 102;AltName: Full=Core
DE   2-branching enzyme;AltName: Full=Core2-GlcNAc-transferase; Short=C2GNT;
DE   (MOUSE19.PE714).
GN   Name=Gcnt1;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE19.PE714.
CC       Mus musculus chromosome 19 NCBIM37  sequence 1..61342430 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:GCNT1_MOUSE
CC   -!- FUNCTION: Forms critical branches in O-glycans.
CC   -!- CATALYTIC ACTIVITY: UDP-N-acetyl-D-glucosamine + beta-D-
CC       galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-
CC       galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-
CC       galactosaminyl-R.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass type
CC       II membrane protein.
CC   -!- TISSUE SPECIFICITY: Expressed in kidney, liver, stomach, spleen,
CC       lung and brain.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 14 family.
CC   -!- WEB RESOURCE: Name=Functional Glycomics Gateway - GTase; Note=core
CC       2 beta 6 GlcNAc T1;
CC       URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_574";
CC   -!- GENE_FAMILY: HOG000293251 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000038843;ENSMUST00000067276;ENSMUSP00000069023.
DR   EMBL; AK045216; - ;
DR   EMBL; BC039126; - ;
DR   EMBL; D87332; - ;
DR   EMBL; D87333; - ;
DR   EMBL; U19265; - ;
DR   UniProtKB/Swiss-Prot; Q09324; O35981; Q8BRB2; -.
DR   EMBL; U19265; AAA60948.1; -; mRNA.
DR   EMBL; D87332; BAA22998.1; -; mRNA.
DR   EMBL; D87333; BAA22999.1; -; mRNA.
DR   EMBL; AK045216; BAC32265.1; -; mRNA.
DR   IPI; IPI00311895; -.
DR   RefSeq; NP_001129956.1; NM_001136484.1.
DR   RefSeq; NP_034395.2; NM_010265.3.
DR   RefSeq; NP_775618.1; NM_173442.3.
DR   UniGene; Mm.244825; -.
DR   PDB; 2GAK; X-ray; 2.00 A; A/B=38-428.
DR   PDB; 2GAM; X-ray; 2.70 A; A/B/C/D=38-428.
DR   PDBsum; 2GAK; -.
DR   PDBsum; 2GAM; -.
DR   ProteinModelPortal; Q09324; -.
DR   STRING; Q09324; -.
DR   CAZy; GT14; Glycosyltransferase Family 14.
DR   PhosphoSite; Q09324; -.
DR   PRIDE; Q09324; -.
DR   Ensembl; ENSMUST00000067276; ENSMUSP00000069023; ENSMUSG00000038843.
DR   Ensembl; ENSMUST00000168606; ENSMUSP00000129033; ENSMUSG00000038843.
DR   Ensembl; ENSMUST00000169897; ENSMUSP00000127835; ENSMUSG00000038843.
DR   GeneID; 14537; -.
DR   CTD; 2650; -.
DR   MGI; MGI:95676; Gcnt1.
DR   eggNOG; maNOG06661; -.
DR   GeneTree; ENSGT00550000074330; -.
DR   InParanoid; Q09324; -.
DR   OrthoDB; EOG4W0XDC; -.
DR   NextBio; 286198; -.
DR   ArrayExpress; Q09324; -.
DR   Bgee; Q09324; -.
DR   CleanEx; MM_GCNT1; -.
DR   Genevestigator; Q09324; -.
DR   GermOnline; ENSMUSG00000038843; Mus musculus.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003829; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; IEDR   InterPro; IPR003406; Glyco_trans_14.
DR   InterPro; IPR003406; Glyco_trans_14.
DR   Pfam; PF02485; Branch; 1.
DR   HOGENOMDNA; MOUSE19.PE714; -.
KW   ENSMUSG000000388435old_1320000031; ENSMUSP000000690231old_1320000031;
KW   Q5D0D8_MOUSE; Q8BRB2_MOUSE; AK045216; BC039126; D87332; D87333; U19265;
KW   3D-structure; Complete proteome; Direct protein sequencing;
KW   Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus;
KW   Membrane; Phosphoprotein; Reference proteome; Signal-anchor;
KW   Transferase; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   428 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MLRNLFRRRL FSCPTKYYFM LLVLSLITFS VLRIHQKPEF FSVRHLELAG DDPYSNVNCT
     KILQGDPEEI QKVKLEILTV QFKKRPRRTP HDYINMTRDC ASFIRTRKYI VEPLTKEEVG
     FPIAYSIVVH HKIEMLDRLL RAIYMPQNFY CIHVDRKAEE SFLAAVQGIA SCFDNVFVAS
     QLESVVYASW SRVKADLNCM KDLYRMNANW KYLINLCGMD FPIKTNLEIV RKLKCSTGEN
     NLETEKMPPN KEERWKKRYT VVDGKLTNTG IVKAPPPLKT PLFSGSAYFV VTREYVGYVL
     ENENIQKLME WAQDTYSPDE FLWATIQRIP EVPGSFPSSN KYDLSDMNAI ARFVKWQYFE
     GHVSNGAPYP PCSGVHVRSV CVFGAGDLSW MLRQHHLFAN KFDMDVDPFA IQCLDEHLRH
     KALENLEH
//

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