(data stored in ACNUC17492 zone)

HOGENOM: MOUSE1_PE2255

ID   MOUSE1_PE2255                        STANDARD;      PRT;   181 AA.
AC   MOUSE1_PE2255; O08850; Q543B1; Q9D0Z2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 5; Short=RGS5;
DE   (MOUSE1.PE2255).
GN   Name=Rgs5;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE1.PE2255.
CC       Mus musculus chromosome 1 NCBIM37  sequence 1..197195432 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS5_MOUSE
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha,
CC       but not to G(s)-alpha.
CC   -!- TISSUE SPECIFICITY: Expressed in heart and muscle.
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000026678;ENSMUST00000027997;ENSMUSP00000027997.
DR   EMBL; AK004165; - ;
DR   EMBL; AK044096; - ;
DR   EMBL; AK054098; - ;
DR   EMBL; BC037683; - ;
DR   EMBL; U67188; - ;
DR   UniProtKB/Swiss-Prot; O08850; Q543B1; Q9D0Z2; -.
DR   EMBL; U67188; AAB50618.1; -; mRNA.
DR   EMBL; AK004165; BAB23201.1; -; mRNA.
DR   EMBL; AK044096; BAC31773.1; -; mRNA.
DR   EMBL; AK054098; BAC35655.1; -; mRNA.
DR   EMBL; BC037683; AAH37683.1; -; mRNA.
DR   IPI; IPI00116374; -.
DR   RefSeq; NP_033089.2; NM_009063.3.
DR   UniGene; Mm.20954; -.
DR   ProteinModelPortal; O08850; -.
DR   SMR; O08850; 44-180.
DR   STRING; O08850; -.
DR   PhosphoSite; O08850; -.
DR   PRIDE; O08850; -.
DR   Ensembl; ENSMUST00000027997; ENSMUSP00000027997; ENSMUSG00000026678.
DR   GeneID; 19737; -.
DR   KEGG; mmu:19737; -.
DR   UCSC; uc007dlm.1; mouse.
DR   CTD; 8490; -.
DR   MGI; MGI:1098434; Rgs5.
DR   eggNOG; maNOG17871; -.
DR   GeneTree; ENSGT00600000084096; -.
DR   InParanoid; O08850; -.
DR   OMA; HSCLERA; -.
DR   OrthoDB; EOG41RPW5; -.
DR   NextBio; 297180; -.
DR   ArrayExpress; O08850; -.
DR   Bgee; O08850; -.
DR   CleanEx; MM_RGS5; -.
DR   Genevestigator; O08850; -.
DR   GermOnline; ENSMUSG00000026678; Mus musculus.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:MGI.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor protein signaling pathway; TAS:MGI.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; MOUSE1.PE2255; -.
KW   ENSMUSG000000266785old_1320000031; ENSMUSP000000279971old_1320000031;
KW   AK004165; AK044096; AK054098; BC037683; U67188;
KW   Complete proteome; Reference proteome; Signal transduction inhibitor.
SQ   SEQUENCE   181 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MCKGLAALPH SCLERAKEIK IKLGILLQKP DSAVDLVIPY NEKPEKPAKA HKPSLEEVLQ
     WRQSLDKLLQ NSYGFASFKS FLKSEFSEEN LEFWVACENY KKIKSPIKMA EKAKQIYEEF
     IQTEAPKEVN IDHFTKDITM KNLVEPSPRS FDLAQKRIYA LMEKDSLPRF VRSEFYKELI
     K
//

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