(data stored in ACNUC8465 zone)

HOGENOM: MOUSE2_PE2924

ID   MOUSE2_PE2924                        STANDARD;      PRT;   236 AA.
AC   MOUSE2_PE2924; Q8VDU1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Rho-related GTP-binding protein RhoV; (MOUSE2.PE2924).
GN   Name=Rhov;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE2.PE2924.
CC       Mus musculus chromosome 2 NCBIM37  sequence 1..181748087 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:RHOV_MOUSE
CC   -!- FUNCTION: Plays a role in the control of the actin cytoskeleton
CC       via activation of the JNK pathway (By similarity).
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SUBUNIT: Interacts with PAK2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic
CC       side (By similarity). Endosome membrane; Lipid-anchor; Cytoplasmic
CC       side (By similarity). Note=Treatment with TNFA activates endosomal
CC       but not plasma membrane RHOV (By similarity).
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
CC   -!- GENE_FAMILY: HOG000233974 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000034226;ENSMUST00000037360;ENSMUSP00000041411.
DR   EMBL; AK036775; - ;
DR   EMBL; AK037170; - ;
DR   EMBL; AL929318; - ;
DR   EMBL; BC021307; - ;
DR   UniProtKB/Swiss-Prot; Q8VDU1; -.
DR   EMBL; AK036775; BAC29571.1; -; mRNA.
DR   EMBL; AK037170; BAC29732.1; -; mRNA.
DR   EMBL; AL929318; CAM25338.1; -; Genomic_DNA.
DR   EMBL; BC021307; AAH21307.1; -; mRNA.
DR   IPI; IPI00123789; -.
DR   RefSeq; NP_663505.1; NM_145530.2.
DR   UniGene; Mm.120274; -.
DR   HSSP; P60763; 2C2H.
DR   ProteinModelPortal; Q8VDU1; -.
DR   SMR; Q8VDU1; 31-208.
DR   STRING; Q8VDU1; -.
DR   PRIDE; Q8VDU1; -.
DR   Ensembl; ENSMUST00000037360; ENSMUSP00000041411; ENSMUSG00000034226.
DR   GeneID; 228543; -.
DR   KEGG; mmu:228543; -.
DR   UCSC; uc008ltm.2; mouse.
DR   CTD; 171177; -.
DR   MGI; MGI:2444227; Rhov.
DR   eggNOG; roNOG13374; -.
DR   GeneTree; ENSGT00560000076971; -.
DR   InParanoid; Q8VDU1; -.
DR   OMA; TFSVQVL; -.
DR   OrthoDB; EOG4255TJ; -.
DR   PhylomeDB; Q8VDU1; -.
DR   NextBio; 379024; -.
DR   ArrayExpress; Q8VDU1; -.
DR   Bgee; Q8VDU1; -.
DR   CleanEx; MM_RHOV; -.
DR   Genevestigator; Q8VDU1; -.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00174; RHO; 1.
DR   TIGRFAMs; TIGR00231; Small_GTP; 1.
DR   PROSITE; PS51420; RHO; 1.
DR   HOGENOMDNA; MOUSE2.PE2924; -.
KW   ENSMUSG000000342265old_1320000031; ENSMUSP000000414111old_1320000031;
KW   AK036775; AK037170; AL929318; BC021307;
KW   Cell membrane; Complete proteome; Endosome; GTP-binding; Lipoprotein;
KW   Magnesium; Membrane; Metal-binding; Nucleotide-binding; Palmitate;
KW   Reference proteome.
SQ   SEQUENCE   236 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MPPRELSEAE PPPLPASTPP PRRRSAPPEL GIKCVLVGDG AVGKSSLIVS YTCNGYPARY
     RPTALDTFSV QVLVDGAPVR IELWDTAGQE DFDRLRSLCY PDTDVFLACF SVVQPSSFQN
     ITEKWLPEIR THNPQAPVLL VGTQADLRDD VNVLIQLDQG GREGPVPQPQ AQGLAEKIRA
     CCYLECSALT QKNLKEVFDS AILSAIEHKA RLEKKLNAKG VRTLSRCRWK KFFCFV
//

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