(data stored in ACNUC30567 zone)

HOGENOM: MOUSE3_PE1737

ID   MOUSE3_PE1737                        STANDARD;      PRT;   798 AA.
AC   MOUSE3_PE1737; Q9DBT5; A2AE28; Q91YI2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=AMP deaminase 2; EC=3.5.4 6;AltName: Full=AMP deaminase
DE   isoform L; (MOUSE3.PE1737).
GN   Name=Ampd2;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE3.PE1737.
CC       Mus musculus chromosome 3 NCBIM37  sequence 1..159599783 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:AMPD2_MOUSE
CC   -!- FUNCTION: AMP deaminase plays a critical role in energy metabolism
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: AMP + H(2)O = IMP + NH(3).
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway;
CC       IMP from AMP: step 1/1.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SIMILARITY: Belongs to the adenosine and AMP deaminases family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH16662.2; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000092200 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000027889;ENSMUST00000102637;ENSMUSP00000099697.
DR   EMBL; AK004759; - ;
DR   EMBL; AK169980; - ;
DR   EMBL; AL671854; - ;
DR   EMBL; BC016662; - ;
DR   EMBL; BC049119; - ;
DR   UniProtKB/Swiss-Prot; Q9DBT5; A2AE28; Q91YI2; -.
DR   EMBL; AK004759; BAB23540.1; -; mRNA.
DR   EMBL; AK169980; BAE41495.1; -; mRNA.
DR   EMBL; AL671854; CAM27248.1; -; Genomic_DNA.
DR   EMBL; BC016662; AAH16662.2; ALT_INIT; mRNA.
DR   EMBL; BC049119; AAH49119.1; -; mRNA.
DR   IPI; IPI00406639; -.
DR   RefSeq; NP_083055.1; NM_028779.4.
DR   UniGene; Mm.274335; -.
DR   ProteinModelPortal; Q9DBT5; -.
DR   SMR; Q9DBT5; 137-784.
DR   STRING; Q9DBT5; -.
DR   PhosphoSite; Q9DBT5; -.
DR   PRIDE; Q9DBT5; -.
DR   Ensembl; ENSMUST00000102637; ENSMUSP00000099697; ENSMUSG00000027889.
DR   Ensembl; ENSMUST00000102638; ENSMUSP00000099698; ENSMUSG00000027889.
DR   GeneID; 109674; -.
DR   KEGG; mmu:109674; -.
DR   UCSC; uc008qxz.1; mouse.
DR   CTD; 271; -.
DR   MGI; MGI:88016; Ampd2.
DR   GeneTree; ENSGT00390000008190; -.
DR   InParanoid; Q9DBT5; -.
DR   OrthoDB; EOG41JZBP; -.
DR   PhylomeDB; Q9DBT5; -.
DR   NextBio; 362553; -.
DR   ArrayExpress; Q9DBT5; -.
DR   Bgee; Q9DBT5; -.
DR   CleanEx; MM_AMPD2; -.
DR   Genevestigator; Q9DBT5; -.
DR   GermOnline; ENSMUSG00000027889; Mus musculus.
DR   GO; GO:0003876; F:AMP deaminase activity; IEA:EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006144; P:purine base metabolic process; IEA:InterPro.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR001365; A/AMP_deaminase.
DR   InterPro; IPR006329; AMP_deaminase.
DR   InterPro; IPR016297; AMP_deaminase_met.
DR   Pfam; PF00962; A_deaminase; 1.
DR   PIRSF; PIRSF001251; AMP_deaminase_met; 1.
DR   TIGRFAMs; TIGR01429; AMP_deaminase; 1.
DR   PROSITE; PS00485; A_DEAMINASE; 1.
DR   HOGENOMDNA; MOUSE3.PE1737; -.
KW   ENSMUSG000000278895old_1320000031; ENSMUSP000000996971old_1320000031;
KW   A2AE22_MOUSE; A2AE25_MOUSE; AK004759; AK169980; AL671854; BC016662;
KW   BC049119;
KW   Acetylation; Complete proteome; Hydrolase; Metal-binding;
KW   Nucleotide metabolism; Phosphoprotein; Reference proteome; Zinc.
SQ   SEQUENCE   798 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MASEARSGLG ASPLQSARSL PGNAPCLKHF PLDLRTSMDG KCKEIAEELF SRSLAESELR
     SAPYEFPEES PIEQLEERRQ RLERQISQDV KLEPDILLRA KQDFLKTDSD SDLQLYKEQG
     EGQGDRGLWE RDVVLEREFQ RVIISGEEKC GVPFTDLLDA AKSVVRALFI REKYMALSLQ
     SFCPTTRRYL QQLAEKPLET RTYEQSPDTP VSADAPVHPP ALEQHPYEHC EPSAMPGDLG
     LGLRMVRGVV HVYTRRDPDE HCPEVELPYP DLQEFVADVN VLMALIINGP IKSFCYRRLQ
     YLSSKFQMHV LLNEMKELAA QKKVPHRDFY NIRKVDTHIH ASSCMNQKHL LRFIKRAMKR
     HLEEIVHVEQ GREQTLREVF ESMNLTAYDL SVDTLDVHAD RNTFHRFDKF NAKYNPIGES
     VLREIFIKTD NKISGKYFAH IIKEVMADLE ESKYQNAELR LSIYGRSRDE WDKLARWAVN
     HKVHSPNVRW LVQVPRLFDV YRTKGQLANF QEMLENIFLP LFEATVHPAS HPELHLFLEH
     VDGFDSVDDE SKPENHVFNL ESPLPEAWVE EDNPPYAYYL YYTFANMAML NHLRRQRGFH
     TFVLRPHCGE AGPIHHLVSA FMLAENISHG LLLRKAPVLQ YLYYLAQIGI AMSPLSNNSL
     FLSYHRNPLP EYLSRGLMVS LSTDDPLQFH FTKEPLMEEY SIATQVWKLS SCDMCELARN
     SVLMSGFSHK VKSHWLGPNY TKEGPEGNDI RRTNVPDIRV GYRYETLCQE LALITQAVQS
     EMLETIPEEV GIVMSPGP
//

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