(data stored in ACNUC24361 zone)

HOGENOM: MOUSE5_PE2908

ID   MOUSE5_PE2908                        STANDARD;      PRT;   488 AA.
AC   MOUSE5_PE2908; Q8BGS3; Q7TS88; Q8BJ55; Q9CRN6;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;
DE   (MOUSE5.PE2908).
GN   Name=Zkscan1;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE5.PE2908.
CC       Mus musculus chromosome 5 NCBIM37  sequence 1..152537259 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ZKSC1_MOUSE
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q8BGS3-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8BGS3-2; Sequence=VSP_016958;
CC   -!- PTM: Phosphorylated upon DNA damage, probably by ATM or ATR (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family.
CC   -!- SIMILARITY: Contains 6 C2H2-type zinc fingers.
CC   -!- SIMILARITY: Contains 1 KRAB domain.
CC   -!- SIMILARITY: Contains 1 SCAN box domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC27539.1; Type=Frameshift; Positions=479;
CC   -!- GENE_FAMILY: HOG000234619 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000029729;ENSMUST00000066617;ENSMUSP00000068480.
DR   EMBL; AK020039; - ;
DR   EMBL; AK028932; - ;
DR   EMBL; AK031759; - ;
DR   EMBL; AK036807; - ;
DR   EMBL; AK054323; - ;
DR   EMBL; AK131148; - ;
DR   EMBL; AK135999; - ;
DR   EMBL; BC052441; - ;
DR   UniProtKB/Swiss-Prot; Q8BGS3; Q7TS88; Q8BJ55; Q9CRN6; -.
DR   EMBL; AK131148; BAD21398.1; -; mRNA.
DR   EMBL; AK020039; BAB31975.1; -; mRNA.
DR   EMBL; AK028932; BAC26200.1; -; mRNA.
DR   EMBL; AK031759; BAC27539.1; ALT_FRAME; mRNA.
DR   EMBL; AK036807; BAC29584.1; -; mRNA.
DR   EMBL; AK054323; BAC35730.1; -; mRNA.
DR   EMBL; AK135999; BAE22767.1; -; mRNA.
DR   EMBL; BC052441; AAH52441.1; -; mRNA.
DR   IPI; IPI00221695; -.
DR   IPI; IPI00408477; -.
DR   RefSeq; NP_084145.1; NM_029869.1.
DR   RefSeq; NP_598667.2; NM_133906.4.
DR   UniGene; Mm.213114; -.
DR   ProteinModelPortal; Q8BGS3; -.
DR   SMR; Q8BGS3; 50-138, 343-543.
DR   PhosphoSite; Q8BGS3; -.
DR   PRIDE; Q8BGS3; -.
DR   Ensembl; ENSMUST00000019660; ENSMUSP00000019660; ENSMUSG00000029729.
DR   Ensembl; ENSMUST00000066617; ENSMUSP00000068480; ENSMUSG00000029729.
DR   Ensembl; ENSMUST00000110962; ENSMUSP00000106587; ENSMUSG00000029729.
DR   Ensembl; ENSMUST00000110963; ENSMUSP00000106588; ENSMUSG00000029729.
DR   GeneID; 74570; -.
DR   KEGG; mmu:74570; -.
DR   UCSC; uc009aej.1; mouse.
DR   UCSC; uc009aek.1; mouse.
DR   CTD; 7586; -.
DR   MGI; MGI:1921820; Zkscan1.
DR   eggNOG; roNOG06261; -.
DR   GeneTree; ENSGT00600000084138; -.
DR   InParanoid; Q8BGS3; -.
DR   OMA; KREQQGR; -.
DR   OrthoDB; EOG4DJJW3; -.
DR   PhylomeDB; Q8BGS3; -.
DR   NextBio; 341125; -.
DR   ArrayExpress; Q8BGS3; -.
DR   Bgee; Q8BGS3; -.
DR   CleanEx; MM_ZKSCAN1; -.
DR   Genevestigator; Q8BGS3; -.
DR   GermOnline; ENSMUSG00000029729; Mus musculus.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral reproduction; IEA:InterPro.
DR   InterPro; IPR001909; Krueppel-associated_box.
DR   InterPro; IPR008916; Retrov_capsid_C.
DR   InterPro; IPR003309; Tscrpt_reg_SCAN.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 6.
DR   Pfam; PF01352; KRAB; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   Pfam; PF00096; zf-C2H2; 6.
DR   SMART; SM00349; KRAB; 1.
DR   SMART; SM00431; SCAN; 1.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   SUPFAM; SSF109640; Krueppel-associated_box; 1.
DR   SUPFAM; SSF47353; Retrov_capsid_C; 1.
DR   PROSITE; PS50805; KRAB; FALSE_NEG.
DR   PROSITE; PS50804; SCAN_BOX; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
DR   HOGENOMDNA; MOUSE5.PE2908; -.
KW   ENSMUSG000000297295old_1320000031; ENSMUSP000000684801old_1320000031;
KW   AK020039; AK028932; AK031759; AK036807; AK054323; AK131148; AK135999;
KW   BC052441;
KW   Alternative splicing; Complete proteome; DNA-binding; Metal-binding;
KW   Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
SQ   SEQUENCE   488 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MMTAESRETT GLSPQAAQEK DGIVIVKVEE EDEEDHMWGQ DSSLQETPPP DPEVFRQRFR
     RFCYQNTFGP REALNRLKEL CHQWLRPEVN SKEQILELLV LEQFLSILPK ELQVWLQEYR
     PDSGEEAVTL LEDLELDLSG QQVPGQVHGP EMLARGVVPL DPVQESSSFD HHETAQSHFK
     HSSRKPRLLS RGSENRNGNE STSKAEVKED STSHGEIAGR FQKEFGEKRE QQGRVVERQQ
     KNPEEKTGKE KKEPGPPTAK EKKPSTGERG PREKGKGLGR SFSLSANFNN TPEEAPSGAK
     THRCDECGKC FTRSSSLIRH KIIHTGEKPY ECNECGKAFS LNSNLVLHQR IHTGEKPHEC
     NECGKAFSHS SNLILHQRIH SGEKPYECNE CGKAFSQSSD LTKHQRIHTG EKPYECSECG
     KAFNRNSYLI LHRRIHTREK PYKCTKCGKA FTRSSTLTLH HRIHARERTS EYSPASLDAF
     GAFLKSCV
//

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