(data stored in ACNUC13676 zone)

HOGENOM: MOUSE5_PE2928

ID   MOUSE5_PE2928                        STANDARD;      PRT;   449 AA.
AC   MOUSE5_PE2928; Q9JKC7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=AP-4 complex subunit mu-1;AltName: Full=AP-4 adapter
DE   complex mu subunit;AltName: Full=Adapter-related protein complex 4 mu-1
DE   subunit;AltName: Full=Mu subunit of AP-4;AltName: Full=Mu-adaptin-related
DE   protein 2; Short=mu-ARP2;AltName: Full=Mu4-adaptin; Short=mu4;
DE   (MOUSE5.PE2928).
GN   Name=Ap4m1;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE5.PE2928.
CC       Mus musculus chromosome 5 NCBIM37  sequence 1..152537259 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:AP4M1_MOUSE
CC   -!- FUNCTION: Subunit of novel type of clathrin- or non-clathrin-
CC       associated protein coat involved in targeting proteins from the
CC       trans-Golgi network (TGN) to the endosomal-lysosomal system (By
CC       similarity).
CC   -!- SUBUNIT: Adapter-like complex 4 (AP-4) is an heterotetramer
CC       composed of two large adaptins (epsilon-type subunit AP4E1 and
CC       beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1)
CC       and a small adaptin (sigma-type AP4S1). Interacts with the C-
CC       terminal domain of GRID2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network (By
CC       similarity). Membrane, coated pit (By similarity). Note=Associated
CC       with the trans-Golgi network. Found in soma and dendritic shafts
CC       of neuronal cells (By similarity).
CC   -!- SIMILARITY: Belongs to the adaptor complexes medium subunit
CC       family.
CC   -!- SIMILARITY: Contains 1 MHD (mu homology) domain.
CC   -!- GENE_FAMILY: HOG000173245 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000019518;ENSMUST00000019662;ENSMUSP00000019662.
DR   EMBL; AF242858; - ;
DR   EMBL; AK031638; - ;
DR   EMBL; AY912459; - ;
DR   EMBL; AY912460; - ;
DR   EMBL; AY912461; - ;
DR   EMBL; AY912462; - ;
DR   EMBL; AY912463; - ;
DR   EMBL; AY912464; - ;
DR   EMBL; AY912465; - ;
DR   EMBL; AY912466; - ;
DR   EMBL; AY912467; - ;
DR   EMBL; AY912468; - ;
DR   EMBL; AY912469; - ;
DR   EMBL; AY912470; - ;
DR   EMBL; AY912471; - ;
DR   EMBL; AY912472; - ;
DR   EMBL; AY912473; - ;
DR   EMBL; AY912474; - ;
DR   EMBL; AY912475; - ;
DR   EMBL; AY912476; - ;
DR   EMBL; AY912477; - ;
DR   EMBL; AY912478; - ;
DR   EMBL; AY912479; - ;
DR   EMBL; AY912480; - ;
DR   EMBL; AY912481; - ;
DR   EMBL; BC011174; - ;
DR   UniProtKB/Swiss-Prot; Q9JKC7; -.
DR   EMBL; AF242858; AAF63513.1; -; mRNA.
DR   EMBL; BC011174; AAH11174.1; -; mRNA.
DR   IPI; IPI00122829; -.
DR   RefSeq; NP_067367.3; NM_021392.4.
DR   UniGene; Mm.113205; -.
DR   ProteinModelPortal; Q9JKC7; -.
DR   SMR; Q9JKC7; 1-449.
DR   STRING; Q9JKC7; -.
DR   PhosphoSite; Q9JKC7; -.
DR   PRIDE; Q9JKC7; -.
DR   Ensembl; ENSMUST00000019662; ENSMUSP00000019662; ENSMUSG00000019518.
DR   GeneID; 11781; -.
DR   KEGG; mmu:11781; -.
DR   UCSC; uc009aev.2; mouse.
DR   CTD; 9179; -.
DR   MGI; MGI:1337063; Ap4m1.
DR   GeneTree; ENSGT00530000062779; -.
DR   InParanoid; Q9JKC7; -.
DR   OMA; CGNANPH; -.
DR   PhylomeDB; Q9JKC7; -.
DR   NextBio; 279583; -.
DR   ArrayExpress; Q9JKC7; -.
DR   Bgee; Q9JKC7; -.
DR   CleanEx; MM_AP4M1; -.
DR   Genevestigator; Q9JKC7; -.
DR   GermOnline; ENSMUSG00000019518; Mus musculus.
DR   GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR   GO; GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.
DR   GO; GO:0005802; C:trans-Golgi network; TAS:MGI.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:MGI.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:MGI.
DR   InterPro; IPR022775; AP_mu_sigma_su.
DR   InterPro; IPR001392; Clathrin_mu.
DR   InterPro; IPR008968; Clathrin_mu_C.
DR   InterPro; IPR018240; Clathrin_mu_CS.
DR   InterPro; IPR011012; Longin-like.
DR   Pfam; PF00928; Adap_comp_sub; 1.
DR   Pfam; PF01217; Clat_adaptor_s; 1.
DR   PIRSF; PIRSF005992; Clathrin_mu; 1.
DR   PRINTS; PR00314; CLATHRINADPT.
DR   SUPFAM; SSF49447; AP50; 1.
DR   SUPFAM; SSF64356; Longin_like; 1.
DR   PROSITE; PS00990; CLAT_ADAPTOR_M_1; FALSE_NEG.
DR   PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR   PROSITE; PS51072; MHD; 1.
DR   HOGENOMDNA; MOUSE5.PE2928; -.
KW   ENSMUSG000000195185old_1320000031; ENSMUSP000000196621old_1320000031;
KW   Q2TFM4_MOUSE; Q2TFM7_MOUSE; Q2TFM8_MOUSE; Q2TFM9_MOUSE; Q2TFN0_MOUSE;
KW   Q2TFN6_MOUSE; Q2TFN8_MOUSE; Q8CD17_MOUSE; AF242858; AK031638; AY912459;
KW   AY912461; AY912462; AY912463; AY912464; AY912465; AY912466; AY912467;
KW   AY912469; AY912470; AY912471; AY912472; AY912473; AY912474; AY912475;
KW   AY912477; AY912478; AY912479; AY912480; AY912481; BC011174;
KW   Coated pit; Complete proteome; Golgi apparatus; Membrane;
KW   Phosphoprotein; Protein transport; Reference proteome; Transport.
SQ   SEQUENCE   449 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MISQFFILSS KGDPLIYKDF RGDSGGRDVA ELFYRKLTGL PGGESPVVMY HGDRHFIHIR
     HSGLYLVATT LENVSPFSLL ELLSRLATLL GDYCGSLNEG TISRNVALVY ELLDEVLDYG
     YVQTTSTEML RNFIQTEAVV SKPFSLFDLS SVGLFGAETQ QNKVAPSSAA SRPVLSSRSD
     QSQKNEVFLD VVERLSVLIA SNGSLLKVDV QGEIRLKSFL PSGSEICIGL TEEFCVGKSE
     LRGYGPGIRV DEVSFHSSVN LDEFESHRIL RLQPPQGELT VMRYQLSDDL PSPLPFRLFP
     SVQWDQGSGR LQVYLKLRCD LPPKSQALNI HLHLPLPRGV ISLSQELSSP DQKAELGEGA
     LHWDLPRVQG GSQLSGLFQM DVPGLQGLPN HGPSPLGLGP ASLSFELPRH TCSGLQVRFL
     RLSFSACGNA NPHKWVRHLS HSNAYVIRI
//

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