(data stored in ACNUC10964 zone)

HOGENOM: MOUSE5_PE3054

ID   MOUSE5_PE3054                        STANDARD;      PRT;   459 AA.
AC   MOUSE5_PE3054; Q8CFD4; Q8BLI6; Q8BUQ7;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Sorting nexin-8; (MOUSE5.PE3054).
GN   Name=Snx8;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE5.PE3054.
CC       Mus musculus chromosome 5 NCBIM37  sequence 1..152537259 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:SNX8_MOUSE
CC   -!- FUNCTION: May be involved in several stages of intracellular
CC       trafficking. May play a role in intracellular protein transport
CC       from early endosomes to the trans-Golgi network (By similarity).
CC   -!- SUBCELLULAR LOCATION: Early endosome membrane; Peripheral membrane
CC       protein; Cytoplasmic side (By similarity). Note=Colocalizes with
CC       retromer components (By similarity).
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC   -!- SIMILARITY: Contains 1 PX (phox homology) domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC32202.1; Type=Erroneous initiation;
CC       Sequence=BAE28549.1; Type=Erroneous initiation;
CC   -!- GENE_FAMILY: HOG000252992 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000029560;ENSMUST00000031539;ENSMUSP00000031539.
DR   EMBL; AK045061; - ;
DR   EMBL; AK082871; - ;
DR   EMBL; AK148429; - ;
DR   EMBL; AK156817; - ;
DR   EMBL; AK161672; - ;
DR   EMBL; BC037599; - ;
DR   UniProtKB/Swiss-Prot; Q8CFD4; Q8BLI6; Q8BUQ7; -.
DR   EMBL; BC037599; AAH37599.1; -; mRNA.
DR   EMBL; AK045061; BAC32202.1; ALT_INIT; mRNA.
DR   EMBL; AK082871; BAC38662.1; -; mRNA.
DR   EMBL; AK148429; BAE28549.1; ALT_INIT; mRNA.
DR   IPI; IPI00319079; -.
DR   RefSeq; NP_758481.1; NM_172277.2.
DR   UniGene; Mm.27098; -.
DR   ProteinModelPortal; Q8CFD4; -.
DR   SMR; Q8CFD4; 77-173.
DR   PhosphoSite; Q8CFD4; -.
DR   PRIDE; Q8CFD4; -.
DR   Ensembl; ENSMUST00000031539; ENSMUSP00000031539; ENSMUSG00000029560.
DR   GeneID; 231834; -.
DR   KEGG; mmu:231834; -.
DR   UCSC; uc009ahq.1; mouse.
DR   CTD; 29886; -.
DR   MGI; MGI:2443816; Snx8.
DR   GeneTree; ENSGT00460000041594; -.
DR   InParanoid; Q8CFD4; -.
DR   OMA; LYCLHQE; -.
DR   OrthoDB; EOG42JNRD; -.
DR   NextBio; 380783; -.
DR   ArrayExpress; Q8CFD4; -.
DR   Bgee; Q8CFD4; -.
DR   CleanEx; MM_SNX8; -.
DR   Genevestigator; Q8CFD4; -.
DR   GermOnline; ENSMUSG00000029560; Mus musculus.
DR   GO; GO:0031901; C:early endosome membrane; ISS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0034498; P:early endosome to Golgi transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   InterPro; IPR001683; Phox.
DR   Gene3D; G3DSA:3.30.1520.10; PX; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX; 1.
DR   PROSITE; PS50195; PX; 1.
DR   HOGENOMDNA; MOUSE5.PE3054; -.
KW   ENSMUSG000000295605old_1320000031; ENSMUSP000000315391old_1320000031;
KW   Q3TT02_MOUSE; Q3U0I9_MOUSE; AK045061; AK082871; AK148429; AK156817;
KW   BC037599;
KW   Complete proteome; Endosome; Lipid-binding; Membrane; Phosphoprotein;
KW   Protein transport; Reference proteome; Transport.
SQ   SEQUENCE   459 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MTGRAMDPLP SPAVAAAAEA EADEEADPPA TGPRTSQVTE WRALDPGRMQ MPQGNPLLLS
     YTLQELLAKD TVQVELIPEK KGLFLKHVEY EVSSQRFKSS VYRRYNDFVV FHEVLLHKFP
     YRMVPALPPK RVLGADREFI EGRRRALKRF INLVARHPPF SEDVLLKLFL SFSGSDVQHK
     LKEAAQCVGD EFMNCKLAAR AKDFLPADIQ TQFAMSRELI RNVYNSFYKL RDRAERIASR
     AIDNAADLLI FGKELSALGS DTTPLPSWAA LHLSTWGSLK QALKGLSVEF ALLADRAAQQ
     GKKEENDVVE KLNLFLDLLQ SYKDLCERHE KGVLHKHQRA LHKYGLMKRQ MMSAAHGREP
     ESVEQLESRI VEQENVIQTM ELRNYFSLYC LHQETQLVHV YLPLTSHILG AFVNSQIQGH
     KEMSKVWNDL KPKLSCLFAG PHSVLTPPRS PQEDGVCPH
//

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