(data stored in ACNUC6288 zone)

HOGENOM: MOUSE5_PE472

ID   MOUSE5_PE472                         STANDARD;      PRT;   524 AA.
AC   MOUSE5_PE472; Q61749; Q3TYW7; Q61748; Q8VC35;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Translation initiation factor eIF-2B subunit delta;AltName:
DE   Full=eIF-2B GDP-GTP exchange factor subunit delta; (MOUSE5.PE472).
GN   Name=Eif2b4; Synonyms=Eif2b, Eif2bd, Jgr1a;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE5.PE472.
CC       Mus musculus chromosome 5 NCBIM37  sequence 1..152537259 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:EI2BD_MOUSE
CC   -!- FUNCTION: Catalyzes the exchange of eukaryotic initiation factor
CC       2-bound GDP for GTP.
CC   -!- SUBUNIT: Complex of five different subunits; alpha, beta, gamma,
CC       delta and epsilon.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q61749-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q61749-2; Sequence=VSP_001434;
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits
CC       family.
CC   -!- GENE_FAMILY: HOG000176924 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000029145;ENSMUST00000077693;ENSMUSP00000076875.
DR   EMBL; AK158282; - ;
DR   EMBL; BC021884; - ;
DR   EMBL; CH466524; - ;
DR   EMBL; M98035; - ;
DR   EMBL; M98036; - ;
DR   UniProtKB/Swiss-Prot; Q61749; Q3TYW7; Q61748; Q8VC35; -.
DR   EMBL; M98036; AAA68047.1; -; mRNA.
DR   EMBL; M98035; AAA68046.1; -; mRNA.
DR   EMBL; AK158282; BAE34444.1; -; mRNA.
DR   EMBL; CH466524; EDL37345.1; -; Genomic_DNA.
DR   EMBL; BC021884; AAH21884.1; -; mRNA.
DR   IPI; IPI00124879; -.
DR   IPI; IPI00221819; -.
DR   PIR; A55146; A55146.
DR   RefSeq; NP_001120827.1; NM_001127355.1.
DR   RefSeq; NP_001120828.1; NM_001127356.1.
DR   RefSeq; NP_034252.2; NM_010122.2.
DR   UniGene; Mm.29394; -.
DR   ProteinModelPortal; Q61749; -.
DR   STRING; Q61749; -.
DR   PhosphoSite; Q61749; -.
DR   PRIDE; Q61749; -.
DR   Ensembl; ENSMUST00000077693; ENSMUSP00000076875; ENSMUSG00000029145.
DR   Ensembl; ENSMUST00000114603; ENSMUSP00000110250; ENSMUSG00000029145.
DR   Ensembl; ENSMUST00000166769; ENSMUSP00000130880; ENSMUSG00000029145.
DR   GeneID; 13667; -.
DR   KEGG; mmu:13667; -.
DR   UCSC; uc008wxk.2; mouse.
DR   CTD; 8890; -.
DR   MGI; MGI:95300; Eif2b4.
DR   GeneTree; ENSGT00550000075009; -.
DR   PhylomeDB; Q61749; -.
DR   ArrayExpress; Q61749; -.
DR   Bgee; Q61749; -.
DR   Genevestigator; Q61749; -.
DR   GermOnline; ENSMUSG00000029145; Mus musculus.
DR   GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.
DR   GO; GO:0042552; P:myelination; ISS:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
DR   InterPro; IPR000649; IF-2B-related.
DR   PANTHER; PTHR10233; IF-2B_related; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   HOGENOMDNA; MOUSE5.PE472; -.
KW   ENSMUSG000000291455old_1320000031; ENSMUSP000000768751old_1320000031;
KW   Q3TYW7_MOUSE; AK158282; BC021884; CH466524; M98035; M98036;
KW   Alternative splicing; Complete proteome; Initiation factor;
KW   Phosphoprotein; Protein biosynthesis; Reference proteome.
SQ   SEQUENCE   524 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAAVAVAVRE ESRSEMKTEL SPRPGAAGRE LTQEEKLQLR KEKKQQKKKR KEEKGADQEI
     GSAVSAAQRQ DPIRELPGPG SQLGGTAGEK LPAGRSKAEL RAERRAKQEA ERALKQARKG
     EQGGVPPQAC PSTAGETTSG VKRVPEHTPA DDPTLLRRLL RKPDRQQVPT RKDYGSKVSL
     FSHLPQYSRQ SSLTQYMSIP SSVIHPAMVR LGLQYSQGLI SGSNARCIAL LHALQQVIQD
     YTTPPSEELS RDLVNKLKPY ISFLTQCRPM SASMCNAIKF LTKEVTGMSS SKREEEAKSE
     LREALDRYVQ EKIVLAAQAI SRFASTKISD GDVILVYGCS SLVSRILQEA RVEGRRFRVV
     VVDSRPRLEG RHMLHSLVRA GVPTSYLLIP AASYVLPEVS KVLLGAHALL ANGSVMSRVG
     TAQLALVARA HNVPVLVCCE TYKFCERVQT DAFVSNELDD PDDLQCKRGD QVALANWQSH
     PSLRLLNLVY DVTPPELVDL VITELGMIPC SSVPVVLRVK SSDQ
//

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