(data stored in ACNUC21562 zone)

HOGENOM: MOUSE7_PE1800

ID   MOUSE7_PE1800                        STANDARD;      PRT;   302 AA.
AC   MOUSE7_PE1800; Q91WW3;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Mas-related G-protein coupled receptor member A3;
DE   (MOUSE7.PE1800).
GN   Name=Mrgpra3; Synonyms=Mrga3;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE7.PE1800.
CC       Mus musculus chromosome 7 NCBIM37  sequence 1..152524553 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:MRGA3_MOUSE
CC   -!- FUNCTION: Orphan receptor. May be a receptor for RFamide-family
CC       neuropeptides such as NPFF and NPAF, which are analgesic in vivo.
CC       May regulate nociceptor function and/or development, including the
CC       sensation or modulation of pain (By similarity). Activated by the
CC       antimalarial drug chloroquine. Mediates chloroquine-induced itch,
CC       in an histamine-independent manner.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Expressed exclusively in dorsal root ganglia
CC       and nodose ganglia. Expressed in a subset of sensory neurons that
CC       includes nociceptors. Expressed in the subclass of non-peptidergic
CC       sensory neurons that are IB4(+) and VR1(-).
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Mas subfamily.
CC   -!- GENE_FAMILY: HOG000015412 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000078698;ENSMUST00000046797;ENSMUSP00000047578.
DR   EMBL; AY042193; - ;
DR   UniProtKB/Swiss-Prot; Q91WW3; -.
DR   EMBL; AY042193; AAK91789.1; -; mRNA.
DR   IPI; IPI00128452; -.
DR   RefSeq; NP_694707.2; NM_153067.2.
DR   UniGene; Mm.240142; -.
DR   ProteinModelPortal; Q91WW3; -.
DR   SMR; Q91WW3; 96-127.
DR   STRING; Q91WW3; -.
DR   PRIDE; Q91WW3; -.
DR   Ensembl; ENSMUST00000046797; ENSMUSP00000047578; ENSMUSG00000078698.
DR   GeneID; 233222; -.
DR   KEGG; mmu:233222; -.
DR   UCSC; uc009haj.2; mouse.
DR   CTD; 233222; -.
DR   MGI; MGI:2684085; Mrgpra3.
DR   eggNOG; maNOG18315; -.
DR   GeneTree; ENSGT00550000074531; -.
DR   InParanoid; Q91WW3; -.
DR   OMA; ISTERCM; -.
DR   OrthoDB; EOG451DRQ; -.
DR   PhylomeDB; Q91WW3; -.
DR   NextBio; 381631; -.
DR   Bgee; Q91WW3; -.
DR   CleanEx; MM_MRGPRA3; -.
DR   Genevestigator; Q91WW3; -.
DR   GermOnline; ENSMUSG00000039854; Mus musculus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   InterPro; IPR000276; 7TM_GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_supfam.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   HOGENOMDNA; MOUSE7.PE1800; -.
KW   ENSMUSG000000786985old_1320000031; ENSMUSP000000475781old_1320000031;
KW   AY042193;
KW   Acute phase; Cell membrane; Complete proteome;
KW   G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW   Reference proteome; Transducer; Transmembrane; Transmembrane helix.
SQ   SEQUENCE   302 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MNETIPGSID IETLIPDLMI IIFGLVGLTG NAIVFWLLGF RMHRTAFLVY ILNLALADFL
     FLLCHIINST VDLLKFTLPK GIFAFCFHTI KRVLYITGLS MLSAISTERC LSVLCPIWYH
     CRRPEHTSTV MCAVIWVLSL LICILDGYFC GYLDNHYFNY SVCQAWDIFI GAYLMFLFVV
     LCLSTLALLA RLFCGARNMK FTRLFVTIML TVLVFLLCGL PWGITWFLLF WIAPGVFVLD
     YSPLLVLTAI NSCANPIIYF FVGSFRQRLN KQTLKMVLQK ALQDTPETPE NMVEMSRNKA
     EP
//

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