(data stored in ACNUC30567 zone)

HOGENOM: MOUSE7_PE2314

ID   MOUSE7_PE2314                        STANDARD;      PRT;   526 AA.
AC   MOUSE7_PE2314; Q6P8H8; E9Q3H5; Q3TKP5;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2
DE   alpha-1,3-glucosyltransferase; EC=2.4.1 -;AltName: Full=Asparagine-linked
DE   glycosylation protein 8 homolog;AltName:
DE   Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase;
DE   (MOUSE7.PE2314).
GN   Name=Alg8; Synonyms=Gm1089;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE7.PE2314.
CC       Mus musculus chromosome 7 NCBIM37  sequence 1..152524553 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:ALG8_MOUSE
CC   -!- FUNCTION: Adds the second glucose residue to the lipid-linked
CC       oligosaccharide precursor for N-linked glycosylation. Transfers
CC       glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the
CC       lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By
CC       similarity).
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the ALG6/ALG8 glucosyltransferase family.
CC   -!- GENE_FAMILY: HOG000168174 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000035704;ENSMUST00000098300;ENSMUSP00000095901.
DR   EMBL; AK166755; - ;
DR   EMBL; AK166897; - ;
DR   EMBL; BC061244; - ;
DR   EMBL; CH466531; - ;
DR   UniProtKB/Swiss-Prot; Q6P8H8; E9Q3H5; Q3TKP5; -.
DR   EMBL; AK166755; BAE38996.1; -; mRNA.
DR   EMBL; AK166897; BAE39100.1; -; mRNA.
DR   EMBL; AC155933; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH466531; EDL16291.1; -; Genomic_DNA.
DR   EMBL; BC061244; AAH61244.1; -; mRNA.
DR   IPI; IPI00396695; -.
DR   RefSeq; NP_950200.2; NM_199035.2.
DR   UniGene; Mm.279683; -.
DR   UniGene; Mm.407368; -.
DR   STRING; Q6P8H8; -.
DR   CAZy; GT57; Glycosyltransferase Family 57.
DR   PRIDE; Q6P8H8; -.
DR   Ensembl; ENSMUST00000098300; ENSMUSP00000095901; ENSMUSG00000035704.
DR   GeneID; 381903; -.
DR   MGI; MGI:2141959; Alg8.
DR   GeneTree; ENSGT00550000074967; -.
DR   InParanoid; Q6P8H8; -.
DR   OrthoDB; EOG4XKV6N; -.
DR   ArrayExpress; Q6P8H8; -.
DR   Bgee; Q6P8H8; -.
DR   Genevestigator; Q6P8H8; -.
DR   GermOnline; ENSMUSG00000035704; Mus musculus.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000033; F:alpha-1,3-mannosyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0006487; P:protein N-linked glycosylation; ISS:UniProtKB.
DR   InterPro; IPR004856; Glyco_trans_ALG6/ALG8.
DR   PANTHER; PTHR12413; Alg6_Alg8; 1.
DR   Pfam; PF03155; Alg6_Alg8; 1.
DR   HOGENOMDNA; MOUSE7.PE2314; -.
KW   ENSMUSG000000357045old_1320000031; ENSMUSP000000959011old_1320000031;
KW   Q3TKP5_MOUSE; AK166755; AK166897; BC061244; CH466531;
KW   Complete proteome; Endoplasmic reticulum; Glycosyltransferase;
KW   Membrane; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
SQ   SEQUENCE   526 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAASGSATAG GHWFSALALG VTLLKCLLIP TYHSTDFEVH RNWLAITHSL PISQWYYEAT
     SEWTLDYPPF FAWFEYALSH IAKYFDQEML NIHNLNYYSS RTLLFQRFSV ILTDALFVYA
     VHECCKCIDG KRTGKDLTEK PKFILSVLLL WNFGLLIVDH IHFQYNGFLS GLLLLSIARL
     FQKRHIEGAL LFAVLLHLKH IYLYVAPAYG VYLLRSYCFT ASKPDGSVRW SSFSVVRVTS
     LGLIVFLVSA LSLGPFLALN QLPQVFSRLF PFKRGLCHAY WAPNFWALYN ALDKVLSVIG
     LKLKLLDPSQ IPRASMTSGL VQQFQHTVLP SVSPLATLIC TLIAILPSVF CLWFKPQGPR
     GFLRCLVLCA LSSFMFGWHV HEKAILLAIL PMSLLSVEKA GDATVFLILA TTGHYSLFPL
     LFTAPELPIK ILLMLLFTVY SISSLKTLFR KEKPLFNWME TVYLLGLGPL EVCCEFLLPF
     TSWKLKYPFI PLLLTSVYCA VGITYAWTRL YASVLTGSLV SKTKKH
//

If you have problems or comments...

PBIL Back to PBIL home page