(data stored in ACNUC26070 zone)

HOGENOM: MOUSE7_PE2411

ID   MOUSE7_PE2411                        STANDARD;      PRT;   103 AA.
AC   MOUSE7_PE2411; Q9WTW2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Potassium voltage-gated channel subfamily E member
DE   3;AltName: Full=MinK-related peptide 2;AltName: Full=Minimum potassium
DE   ion channel-related peptide 2;AltName: Full=Potassium channel subunit
DE   beta MiRP2; (MOUSE7.PE2411).
GN   Name=Kcne3;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE7.PE2411.
CC       Mus musculus chromosome 7 NCBIM37  sequence 1..152524553 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:KCNE3_MOUSE
CC   -!- FUNCTION: Ancillary protein that assembles as a beta subunit with
CC       a voltage-gated potassium channel complex of pore-forming alpha
CC       subunits. Modulates the gating kinetics and enhances stability of
CC       the channel complex. Associated with KCNC4/Kv3.4 is proposed to
CC       form the subthreshold voltage-gated potassium channel in skeletal
CC       muscle and to establish the resting membrane potential (RMP) in
CC       muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal
CC       cAMP-stimulated potassium channel involved in chloride secretion
CC       (By similarity).
CC   -!- SUBUNIT: Associates with KCNC4/Kv3.4. May associate with
CC       KCNQ1/KCLQT1 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the potassium channel KCNE family.
CC   -!- GENE_FAMILY: HOG000113209 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000035165;ENSMUST00000049333;ENSMUSP00000039353.
DR   EMBL; AF076532; - ;
DR   EMBL; AK008744; - ;
DR   EMBL; AK132773; - ;
DR   EMBL; BC004629; - ;
DR   EMBL; CH466531; - ;
DR   EMBL; DQ832280; - ;
DR   UniProtKB/Swiss-Prot; Q9WTW2; -.
DR   EMBL; AF076532; AAD28090.1; -; mRNA.
DR   EMBL; BC004629; AAH04629.1; -; mRNA.
DR   IPI; IPI00123966; -.
DR   RefSeq; NP_001177798.1; NM_001190869.1.
DR   RefSeq; NP_001177799.1; NM_001190870.1.
DR   RefSeq; NP_001177800.1; NM_001190871.1.
DR   RefSeq; NP_001177879.1; NM_001190950.1.
DR   RefSeq; NP_065599.1; NM_020574.5.
DR   UniGene; Mm.282386; -.
DR   ProteinModelPortal; Q9WTW2; -.
DR   STRING; Q9WTW2; -.
DR   TCDB; 8.A.10.3.1; slow voltage-gated K+ channel accessory protein (MinK) family.
DR   PRIDE; Q9WTW2; -.
DR   Ensembl; ENSMUST00000049333; ENSMUSP00000039353; ENSMUSG00000035165.
DR   Ensembl; ENSMUST00000170954; ENSMUSP00000130019; ENSMUSG00000035165.
DR   GeneID; 57442; -.
DR   KEGG; mmu:57442; -.
DR   CTD; 10008; -.
DR   MGI; MGI:1891124; Kcne3.
DR   GeneTree; ENSGT00390000008537; -.
DR   InParanoid; Q9WTW2; -.
DR   OMA; YKSLHAV; -.
DR   OrthoDB; EOG4B5P6P; -.
DR   PhylomeDB; Q9WTW2; -.
DR   NextBio; 313841; -.
DR   ArrayExpress; Q9WTW2; -.
DR   Bgee; Q9WTW2; -.
DR   Genevestigator; Q9WTW2; -.
DR   GermOnline; ENSMUSG00000035165; Mus musculus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR000369; K_chnl_volt-dep_bsu_KCNE.
DR   InterPro; IPR005426; K_chnl_volt-dep_bsu_KCNE3.
DR   Pfam; PF02060; ISK_Channel; 1.
DR   PRINTS; PR01606; KCNE3CHANNEL.
DR   PRINTS; PR00168; KCNECHANNEL.
DR   HOGENOMDNA; MOUSE7.PE2411; -.
KW   ENSMUSG000000351655old_1320000031; ENSMUSP000000393531old_1320000031;
KW   Q545H9_MOUSE; AF076532; AK008744; AK132773; BC004629; CH466531; DQ832280;
KW   Complete proteome; Glycoprotein; Ion transport; Ionic channel;
KW   Membrane; Potassium; Potassium channel; Potassium transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport;
KW   Voltage-gated channel.
SQ   SEQUENCE   103 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     METSNGTETW YMSLHAVLKA LNTTLHSHLL CRPGPGPGPD NQTEDRRASL PGRNDNSYMY
     ILFVMFLFAV TVGSLILGYT RSRKVDKRSD PYHVYIKNRV SMI
//

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