(data stored in ACNUC17492 zone)

HOGENOM: MOUSE7_PE3573

ID   MOUSE7_PE3573                        STANDARD;      PRT;   181 AA.
AC   MOUSE7_PE3573; Q9CQE5; Q9D3L2;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Regulator of G-protein signaling 10; Short=RGS10;
DE   (MOUSE7.PE3573).
GN   Name=Rgs10;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE7.PE3573.
CC       Mus musculus chromosome 7 NCBIM37  sequence 1..152524553 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:RGS10_MOUSE
CC   -!- FUNCTION: Inhibits signal transduction by increasing the GTPase
CC       activity of G protein alpha subunits thereby driving them into
CC       their inactive GDP-bound form. Associates specifically with the
CC       activated forms of the G protein subunits G(i)-alpha and G(z)-
CC       alpha but fails to interact with the structurally and functionally
CC       distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited
CC       by palmitoylation of the G-protein (By similarity).
CC   -!- SIMILARITY: Contains 1 RGS domain.
CC   -!- GENE_FAMILY: HOG000233512 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000030844;ENSMUST00000033133;ENSMUSP00000033133.
DR   EMBL; AK009283; - ;
DR   EMBL; AK009686; - ;
DR   EMBL; AK017314; - ;
DR   EMBL; AK088009; - ;
DR   EMBL; BC109178; - ;
DR   EMBL; CH466531; - ;
DR   UniProtKB/Swiss-Prot; Q9CQE5; Q9D3L2; -.
DR   EMBL; AK009686; BAB26440.1; -; mRNA.
DR   EMBL; AK009283; BAB26193.1; -; mRNA.
DR   EMBL; AK017314; BAB30688.1; -; mRNA.
DR   EMBL; AK088009; BAC40091.1; -; mRNA.
DR   IPI; IPI00132450; -.
DR   RefSeq; NP_080694.1; NM_026418.2.
DR   UniGene; Mm.18635; -.
DR   ProteinModelPortal; Q9CQE5; -.
DR   SMR; Q9CQE5; 30-164.
DR   STRING; Q9CQE5; -.
DR   PhosphoSite; Q9CQE5; -.
DR   PRIDE; Q9CQE5; -.
DR   Ensembl; ENSMUST00000033133; ENSMUSP00000033133; ENSMUSG00000030844.
DR   GeneID; 67865; -.
DR   KEGG; mmu:67865; -.
DR   CTD; 6001; -.
DR   MGI; MGI:1915115; Rgs10.
DR   GeneTree; ENSGT00540000071162; -.
DR   InParanoid; Q9CQE5; -.
DR   OMA; PKSTAKW; -.
DR   OrthoDB; EOG4JM7QV; -.
DR   PhylomeDB; Q9CQE5; -.
DR   NextBio; 325763; -.
DR   ArrayExpress; Q9CQE5; -.
DR   Bgee; Q9CQE5; -.
DR   CleanEx; MM_RGS10; -.
DR   Genevestigator; Q9CQE5; -.
DR   GermOnline; ENSMUSG00000030844; Mus musculus.
DR   GO; GO:0005515; F:protein binding; IPI:MGI.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000342; Regulat_G_prot_signal.
DR   InterPro; IPR024066; Regulat_G_prot_signal_dom1.
DR   InterPro; IPR016137; Regulat_G_prot_signal_superfam.
DR   Gene3D; G3DSA:1.10.196.10; G3DSA:1.10.196.10; 1.
DR   Pfam; PF00615; RGS; 1.
DR   PRINTS; PR01301; RGSPROTEIN.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulat_G_prot_signal_superfam; 1.
DR   PROSITE; PS50132; RGS; 1.
DR   HOGENOMDNA; MOUSE7.PE3573; -.
KW   ENSMUSG000000308445old_1320000031; ENSMUSP000000331331old_1320000031;
KW   Q32MD7_MOUSE; AK009283; AK009686; AK017314; AK088009; BC109178; CH466531;
KW   Complete proteome; Lipoprotein; Palmitate; Phosphoprotein;
KW   Reference proteome; Signal transduction inhibitor.
SQ   SEQUENCE   181 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFTRAVSRLS RKRPPSDIHD GDGSSSSGHQ SLKSTAKWAS SLENLLEDPE GVQRFREFLK
     KEFSEENVLF WLACEDFKKT EDRKQMQEKA KEIYMTFLSN KASSQVNVEG QSRLTEKILE
     EPHPLMFQKL QDQIFNLMKY DSYSRFLKSD LFLKPKRTEE EEEEPPDAQT AAKRASRIYN
     T
//

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