(data stored in ACNUC18777 zone)

HOGENOM: MOUSE8_PE430

ID   MOUSE8_PE430                         STANDARD;      PRT;   284 AA.
AC   MOUSE8_PE430; P51557; Q543A5; Q924Y5; Q9D2G1;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Steroidogenic acute regulatory protein, mitochondrial;
DE   Short=StAR;AltName: Full=Luteinizing hormone-induced protein;AltName:
DE   Full=START domain-containing protein 1; Short=StARD1;Flags: Precursor;
DE   (MOUSE8.PE430).
GN   Name=Star;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE8.PE430.
CC       Mus musculus chromosome 8 NCBIM37  sequence 1..131738871 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:STAR_MOUSE
CC   -!- FUNCTION: Plays a key role in steroid hormone synthesis by
CC       enhancing the metabolism of cholesterol into pregnenolone.
CC       Transporter that binds to and transport cholesterol through the
CC       intermembrane space of the mitochondrion (Probable).
CC   -!- PATHWAY: Steroid metabolism; cholesterol metabolism.
CC   -!- SUBUNIT: May interact with TSPO (By similarity).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion.
CC   -!- TISSUE SPECIFICITY: Expressed within glia and neurons in discrete
CC       regions of the brain.
CC   -!- SIMILARITY: Contains 1 START domain.
CC   -!- GENE_FAMILY: HOG000142452 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000031574;ENSMUST00000033979;ENSMUSP00000033979.
DR   EMBL; AK019725; - ;
DR   EMBL; AK054470; - ;
DR   EMBL; AK136327; - ;
DR   EMBL; AY032730; - ;
DR   EMBL; BC082283; - ;
DR   EMBL; L36062; - ;
DR   UniProtKB/Swiss-Prot; P51557; Q543A5; Q924Y5; Q9D2G1; -.
DR   EMBL; L36062; AAB94783.1; -; mRNA.
DR   EMBL; AY032730; AAK50433.2; -; Genomic_DNA.
DR   EMBL; AK019725; BAB31842.1; -; mRNA.
DR   EMBL; AK054470; BAC35791.1; -; mRNA.
DR   EMBL; AK136327; BAE22934.1; -; mRNA.
DR   EMBL; BC082283; AAH82283.1; -; mRNA.
DR   IPI; IPI00311822; -.
DR   PIR; A55455; A55455.
DR   RefSeq; NP_035615.2; NM_011485.4.
DR   UniGene; Mm.293314; -.
DR   ProteinModelPortal; P51557; -.
DR   SMR; P51557; 65-275.
DR   STRING; P51557; -.
DR   PhosphoSite; P51557; -.
DR   PRIDE; P51557; -.
DR   Ensembl; ENSMUST00000033979; ENSMUSP00000033979; ENSMUSG00000031574.
DR   GeneID; 20845; -.
DR   KEGG; mmu:20845; -.
DR   UCSC; uc009lhb.1; mouse.
DR   CTD; 6770; -.
DR   MGI; MGI:102760; Star.
DR   eggNOG; roNOG04557; -.
DR   GeneTree; ENSGT00530000063139; -.
DR   InParanoid; P51557; -.
DR   OMA; QEGWKKE; -.
DR   OrthoDB; EOG4JWVF2; -.
DR   PhylomeDB; P51557; -.
DR   NextBio; 299611; -.
DR   ArrayExpress; P51557; -.
DR   Bgee; P51557; -.
DR   CleanEx; MM_STAR; -.
DR   Genevestigator; P51557; -.
DR   GermOnline; ENSMUSG00000031574; Mus musculus.
DR   GO; GO:0015485; F:cholesterol binding; IDA:MGI.
DR   GO; GO:0017127; F:cholesterol transporter activity; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IMP:MGI.
DR   GO; GO:0008211; P:glucocorticoid metabolic process; IMP:MGI.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IDA:MGI.
DR   InterPro; IPR000799; StAR.
DR   InterPro; IPR023393; START-like_dom.
DR   InterPro; IPR002913; START_lipid-bd.
DR   Gene3D; G3DSA:3.30.530.20; G3DSA:3.30.530.20; 1.
DR   Pfam; PF01852; START; 1.
DR   PRINTS; PR00978; STARPROTEIN.
DR   SMART; SM00234; START; 1.
DR   PROSITE; PS50848; START; 1.
DR   HOGENOMDNA; MOUSE8.PE430; -.
KW   ENSMUSG000000315745old_1320000031; ENSMUSP000000339791old_1320000031;
KW   AK019725; AK054470; AK136327; AY032730; BC082283; L36062;
KW   Complete proteome; Direct protein sequencing; Lipid transport;
KW   Lipid-binding; Mitochondrion; Phosphoprotein; Reference proteome;
KW   Steroidogenesis; Transit peptide; Transport.
SQ   SEQUENCE   284 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MFLATFKLCA GSSYRHMRNM KGLRHQAVLA IGQELNWRAL GDSSPGWMGQ VRRRSSLLGS
     QLEATLYSDQ ELSYIQQGEV AMQKALGILN NQEGWKKESQ QENGDEVLSK MVPDVGKVFR
     LEVVVDQPMD RLYEELVDRM EAMGEWNPNV KEIKVLQRIG KDTVITHELA AAAAGNLVGP
     RDFVSVRCTK RRGSTCVLAG MATHFGEMPE QSGVIRAEHG PTCMVLHPLA GSPSKTKLTW
     LLSIDLKGWL PKTIINQVLS QTQIEFANHL RKRLEASPAS EAQC
//

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