(data stored in ACNUC25403 zone)

HOGENOM: MOUSE9_PE547

ID   MOUSE9_PE547                         STANDARD;      PRT;   392 AA.
AC   MOUSE9_PE547; Q8CEG0; Q8CB28;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Pannexin-3; (MOUSE9.PE547).
GN   Name=Panx3;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSE9.PE547.
CC       Mus musculus chromosome 9 NCBIM37  sequence 1..124076172 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:PANX3_MOUSE
CC   -!- FUNCTION: Structural component of the gap junctions and the
CC       hemichannels.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Potential). Cell junction, gap junction.
CC   -!- TISSUE SPECIFICITY: Expressed in skin, cartilage, heart, lung,
CC       liver, spleen, thymus and kidney. Not expressed in brain.
CC   -!- PTM: N-glycosylation may play a role in cell surface targeting.
CC   -!- SIMILARITY: Belongs to the pannexin family.
CC   -!- GENE_FAMILY: HOG000063721 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000011118;ENSMUST00000011262;ENSMUSP00000011262.
DR   EMBL; AK028288; - ;
DR   EMBL; AK036933; - ;
DR   EMBL; BC052822; - ;
DR   EMBL; BK000662; - ;
DR   UniProtKB/Swiss-Prot; Q8CEG0; Q8CB28; -.
DR   EMBL; AK028288; BAC25860.1; -; mRNA.
DR   EMBL; AK036933; BAC29644.1; -; mRNA.
DR   EMBL; BC052822; AAH52822.1; -; mRNA.
DR   IPI; IPI00318617; -.
DR   RefSeq; NP_766042.2; NM_172454.2.
DR   UniGene; Mm.217159; -.
DR   PRIDE; Q8CEG0; -.
DR   Ensembl; ENSMUST00000011262; ENSMUSP00000011262; ENSMUSG00000011118.
DR   GeneID; 208098; -.
DR   KEGG; mmu:208098; -.
DR   CTD; 116337; -.
DR   MGI; MGI:1918881; Panx3.
DR   GeneTree; ENSGT00390000009703; -.
DR   InParanoid; Q8CEG0; -.
DR   OMA; MSLAFAQ; -.
DR   OrthoDB; EOG4R7V9Z; -.
DR   PhylomeDB; Q8CEG0; -.
DR   NextBio; 372144; -.
DR   ArrayExpress; Q8CEG0; -.
DR   Bgee; Q8CEG0; -.
DR   CleanEx; MM_PANX3; -.
DR   Genevestigator; Q8CEG0; -.
DR   GermOnline; ENSMUSG00000011118; Mus musculus.
DR   GO; GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055077; F:gap junction hemi-channel activity; ISS:UniProtKB.
DR   GO; GO:0005216; F:ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0034214; P:protein hexamerization; ISS:UniProtKB.
DR   InterPro; IPR000990; Innexin.
DR   Pfam; PF00876; Innexin; 1.
DR   PROSITE; PS51013; PANNEXIN; 1.
DR   HOGENOMDNA; MOUSE9.PE547; -.
KW   ENSMUSG000000111185old_1320000031; ENSMUSP000000112621old_1320000031;
KW   Q6IMP0_MOUSE; AK028288; AK036933; BC052822; BK000662;
KW   Cell junction; Cell membrane; Complete proteome; Gap junction;
KW   Glycoprotein; Ion transport; Ionic channel; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
SQ   SEQUENCE   392 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MSLAHTAAEY MLSDALLPDR RGSRLKGLRL ELPLDKMVKF ITVGFPLLLM SLAFAQEFSS
     GSPISCFSPS NFSVRQAAYV DSSCWDSLAH HTQDKAGQYK VKSLWPHKAL PYSLLALAVA
     MYLPVLLWQY VAVPSLSSDL LFIISELDKS YNRSIRLVQH MLQIRQSSSD PHVFWDELEK
     ARKERYFEFP LLERYLECKQ RSHWLVATYL LRNALLLLFT SATYLYLGQF HLDVFFQDEF
     NCFIKTGLLH DETHVPELIT CRLTSLSVFQ IVSVSSAAIY TILVPVIIYN LTRLCRWDKG
     LLSIYEMLPA FDLLSRKMLG CPINDLNVIL LFLRANISEL ISFSWLSVLS VLKDTTTQKH
     NIDTVVDFMT FVAGLEPSKP KHLTQHTYDE HA
//

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