(data stored in ACNUC21429 zone)

HOGENOM: MOUSEX_PE1962

ID   MOUSEX_PE1962                        STANDARD;      PRT;   638 AA.
AC   MOUSEX_PE1962; Q9QZM0; B1AY62; Q7TSJ8; Q8VDH9;
DT   00-JAN-0000 (Rel. 1, Created)
DT   00-JAN-0000 (Rel. 2, Last sequence update)
DT   00-JAN-0000 (Rel. 3, Last annotation update)
DE   RecName: Full=Ubiquilin-2;AltName: Full=Chap1;AltName: Full=DSK2
DE   homolog;AltName: Full=Protein linking IAP with cytoskeleton 2;
DE   Short=PLIC-2;AltName: Full=Ubiquitin-like product Chap1/Dsk2;
DE   (MOUSEX.PE1962).
GN   Name=Ubqln2; Synonyms=Plic2;
OS   MUS MUSCULUS.
OC   Eukaryota; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia;
OC   Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi;
OC   Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria;
OC   Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae;
OC   Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [0]
RP   -.;
RG   -.;
RL   -.;
CC   -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS MOUSEX.PE1962.
CC       Mus musculus chromosome X NCBIM37  sequence 1..166650296 annotated by
CC       Ensembl
CC   -!- ANNOTATIONS ORIGIN:UBQL2_MOUSE
CC   -!- FUNCTION: Increases the half-life of proteins destined to be
CC       degraded by the proteasome; may modulate proteasome-mediated
CC       protein degradation (By similarity). Links CD47 to vimentin-
CC       containing intermediate filaments of the cytoskeleton.
CC   -!- SUBUNIT: Binds UBE3A and BTRC. Interacts with the 19S proteasome
CC       subunit (By similarity). Binds CD47.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Membrane.
CC       Note=Associated with fibers and membrane-associated.
CC   -!- TISSUE SPECIFICITY: Highly expressed in smooth muscle. Expression
CC       in other tissues is very low.
CC   -!- SIMILARITY: Contains 1 UBA domain.
CC   -!- SIMILARITY: Contains 1 ubiquitin-like domain.
CC   -!- GENE_FAMILY: HOG000234878 [ FAMILY / ALN / TREE ]
DR   HOGENOM:Mus_musculus;ENSMUSG00000050148;ENSMUST00000060714;ENSMUSP00000056888.
DR   EMBL; AF177346; - ;
DR   EMBL; AL844583; - ;
DR   EMBL; BC021824; - ;
DR   EMBL; BC053022; - ;
DR   EMBL; CH466653; - ;
DR   UniProtKB/Swiss-Prot; Q9QZM0; B1AY62; Q7TSJ8; Q8VDH9; -.
DR   EMBL; AF177346; AAF01366.1; -; mRNA.
DR   EMBL; AL844583; CAM18356.1; -; Genomic_DNA.
DR   EMBL; CH466653; EDL31351.1; -; Genomic_DNA.
DR   EMBL; BC021824; AAH21824.1; -; mRNA.
DR   EMBL; BC053022; AAH53022.1; -; mRNA.
DR   IPI; IPI00387416; -.
DR   RefSeq; NP_061268.2; NM_018798.2.
DR   UniGene; Mm.430772; -.
DR   ProteinModelPortal; Q9QZM0; -.
DR   STRING; Q9QZM0; -.
DR   PhosphoSite; Q9QZM0; -.
DR   PRIDE; Q9QZM0; -.
DR   Ensembl; ENSMUST00000060714; ENSMUSP00000056888; ENSMUSG00000050148.
DR   GeneID; 54609; -.
DR   KEGG; mmu:54609; -.
DR   CTD; 29978; -.
DR   MGI; MGI:1860283; Ubqln2.
DR   eggNOG; roNOG04362; -.
DR   GeneTree; ENSGT00390000005720; -.
DR   InParanoid; Q9QZM0; -.
DR   OrthoDB; EOG48KRBD; -.
DR   PhylomeDB; Q9QZM0; -.
DR   NextBio; 311408; -.
DR   ArrayExpress; Q9QZM0; -.
DR   Bgee; Q9QZM0; -.
DR   CleanEx; MM_UBQLN2; -.
DR   Genevestigator; Q9QZM0; -.
DR   GermOnline; ENSMUSG00000050148; Mus musculus.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR006636; STI1_HS-bd.
DR   InterPro; IPR009060; UBA-like.
DR   InterPro; IPR000449; UBA/transl_elong_EF1B_N.
DR   InterPro; IPR015940; UBA/transl_elong_EF1B_N_euk.
DR   InterPro; IPR015496; Ubiquilin.
DR   InterPro; IPR000626; Ubiquitin.
DR   InterPro; IPR019955; Ubiquitin_supergroup.
DR   PANTHER; PTHR10677; Ubiquilin; 1.
DR   Pfam; PF00627; UBA; 1.
DR   Pfam; PF00240; ubiquitin; 1.
DR   SMART; SM00727; STI1; 4.
DR   SMART; SM00165; UBA; 1.
DR   SMART; SM00213; UBQ; 1.
DR   SUPFAM; SSF48371; ARM-type_fold; 1.
DR   SUPFAM; SSF46934; UBA_like; 1.
DR   PROSITE; PS50030; UBA; 1.
DR   PROSITE; PS00299; UBIQUITIN_1; FALSE_NEG.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
DR   HOGENOMDNA; MOUSEX.PE1962; -.
KW   ENSMUSG000000501485old_1320000031; ENSMUSP000000568881old_1320000031;
KW   B1AY62_MOUSE; AF177346; AL844583; BC021824; BC053022; CH466653;
KW   Acetylation; Complete proteome; Cytoplasm; Membrane; Nucleus;
KW   Phosphoprotein; Reference proteome; Repeat.
SQ   SEQUENCE   638 AA;  UNKNOWN MW;  UNKNOWN CRC64;
     MAENGESSGP PRPSRGPAAA PGAASPPAEP KIIKVTVKTP KEKEEFAVPE NSTVQQFKEA
     ISKRFKSQTD QLVLIFAGKI LKDQDTLMQH GIHDGLTVHL VIKSQNRPQG QATTQPSTTA
     GTSTTTTTTT TAAAPAATTS SAPRSSSTPT TTNSSSFGLG SLSSLSNLGL NSPNFTELQN
     QMQQQLLASP EMMIQIMENP FVQSMLSNPD LMRQLIMANP QMQQLIQRNP EISHLLNNPD
     IMRQTLEIAR NPAMMQEMMR NQDLALSNLE SIPGGYNALR RMYTDIQEPM LNAAQEQFGG
     NPFATVGSSS TSGEGTQPSR TENRDPLPNP WAPPPTTQTA ATTTTTTTTS SGSGSGSSSS
     STTAGNTMAA ANYVASIFST PGMQSLLQQI TENPQLIQNM LSAPYMRSMM QSLSQNPDMA
     AQMMLSSPLF TSNPQLQEQM RPQLPNFLQQ MQNPETIAAM SNPRAMQALM QIQQGLQTLA
     TEAPGLIPSF APGVGMGVLG TAITPVGPVT PIGPIGPIVP FTPIGPIGPI GPTGPASSPG
     STGTGIPPAT TVSSSAPTET ISPTSESGPN QQFIQQMVQA LTGGSPPQPP NPEVRFQQQL
     EQLNAMGFLN REANLQALIA TGGDINAAIE RLLGSQPS
//

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